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Non-Union Treatment Based on the “Diamond Concept” Is a Clinically Effective and Safe Treatment Option in Older Adults

BACKGROUND: Patients >60 years suffering from non-unions are often unable to perform activities of daily living and often become dependent on nursing care. Evidence regarding treatment options and outcome is nonexistent. This study sought to determine the clinical effectiveness and safety of one-...

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Autores principales: Tanner, Michael C, Hagelskamp, Saskia, Vlachopoulos, Wasilios, Miska, Matthias, Findeisen, Sebastian, Grimm, Andreas, Schmidmaier, Gerhard, Haubruck, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382610/
https://www.ncbi.nlm.nih.gov/pubmed/32801671
http://dx.doi.org/10.2147/CIA.S241936
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author Tanner, Michael C
Hagelskamp, Saskia
Vlachopoulos, Wasilios
Miska, Matthias
Findeisen, Sebastian
Grimm, Andreas
Schmidmaier, Gerhard
Haubruck, Patrick
author_facet Tanner, Michael C
Hagelskamp, Saskia
Vlachopoulos, Wasilios
Miska, Matthias
Findeisen, Sebastian
Grimm, Andreas
Schmidmaier, Gerhard
Haubruck, Patrick
author_sort Tanner, Michael C
collection PubMed
description BACKGROUND: Patients >60 years suffering from non-unions are often unable to perform activities of daily living and often become dependent on nursing care. Evidence regarding treatment options and outcome is nonexistent. This study sought to determine the clinical effectiveness and safety of one- or two-step non-union therapy in elderly patients. METHODS: This study was a single-site retrospective database analysis of older adults with long bone non-unions treated via “diamond concept”. All medical records of patients receiving surgical treatment of non-unions between 01/01/2010 and 31/12/2016 were reviewed. Clinical and radiological outcome subsequent to non-union therapy were evaluated. RESULTS: A total of 76 patients (37 patients were treated with one-step and 39 patients with Masquelet therapy) suffering from a non-union older than 60 years treated between 01/01/2010 and 31/12/2016 in our institution were included into the current study. Bone consolidation was achieved in 91.9% after one-step and 76.9% after the Masquelet therapy. Analysis of age as a risk factor in the outcome of non-union therapy revealed no significant differences in patients treated with the one-step procedure according to the “diamond concept”. On the contrary, age had a significant negative influence on the outcome of the Masquelet therapy (p = 0.027). CONCLUSION: Non-union therapy according to the “diamond concept” is an effective and reliable treatment option in elderly patients. According to findings of the current study, older adults suffering from an infected non-union benefit from a two-stage procedure, whereas in patients suffering from a non-infected non-union, a one-step surgical treatment is beneficial.
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spelling pubmed-73826102020-08-13 Non-Union Treatment Based on the “Diamond Concept” Is a Clinically Effective and Safe Treatment Option in Older Adults Tanner, Michael C Hagelskamp, Saskia Vlachopoulos, Wasilios Miska, Matthias Findeisen, Sebastian Grimm, Andreas Schmidmaier, Gerhard Haubruck, Patrick Clin Interv Aging Original Research BACKGROUND: Patients >60 years suffering from non-unions are often unable to perform activities of daily living and often become dependent on nursing care. Evidence regarding treatment options and outcome is nonexistent. This study sought to determine the clinical effectiveness and safety of one- or two-step non-union therapy in elderly patients. METHODS: This study was a single-site retrospective database analysis of older adults with long bone non-unions treated via “diamond concept”. All medical records of patients receiving surgical treatment of non-unions between 01/01/2010 and 31/12/2016 were reviewed. Clinical and radiological outcome subsequent to non-union therapy were evaluated. RESULTS: A total of 76 patients (37 patients were treated with one-step and 39 patients with Masquelet therapy) suffering from a non-union older than 60 years treated between 01/01/2010 and 31/12/2016 in our institution were included into the current study. Bone consolidation was achieved in 91.9% after one-step and 76.9% after the Masquelet therapy. Analysis of age as a risk factor in the outcome of non-union therapy revealed no significant differences in patients treated with the one-step procedure according to the “diamond concept”. On the contrary, age had a significant negative influence on the outcome of the Masquelet therapy (p = 0.027). CONCLUSION: Non-union therapy according to the “diamond concept” is an effective and reliable treatment option in elderly patients. According to findings of the current study, older adults suffering from an infected non-union benefit from a two-stage procedure, whereas in patients suffering from a non-infected non-union, a one-step surgical treatment is beneficial. Dove 2020-07-21 /pmc/articles/PMC7382610/ /pubmed/32801671 http://dx.doi.org/10.2147/CIA.S241936 Text en © 2020 Tanner et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Tanner, Michael C
Hagelskamp, Saskia
Vlachopoulos, Wasilios
Miska, Matthias
Findeisen, Sebastian
Grimm, Andreas
Schmidmaier, Gerhard
Haubruck, Patrick
Non-Union Treatment Based on the “Diamond Concept” Is a Clinically Effective and Safe Treatment Option in Older Adults
title Non-Union Treatment Based on the “Diamond Concept” Is a Clinically Effective and Safe Treatment Option in Older Adults
title_full Non-Union Treatment Based on the “Diamond Concept” Is a Clinically Effective and Safe Treatment Option in Older Adults
title_fullStr Non-Union Treatment Based on the “Diamond Concept” Is a Clinically Effective and Safe Treatment Option in Older Adults
title_full_unstemmed Non-Union Treatment Based on the “Diamond Concept” Is a Clinically Effective and Safe Treatment Option in Older Adults
title_short Non-Union Treatment Based on the “Diamond Concept” Is a Clinically Effective and Safe Treatment Option in Older Adults
title_sort non-union treatment based on the “diamond concept” is a clinically effective and safe treatment option in older adults
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382610/
https://www.ncbi.nlm.nih.gov/pubmed/32801671
http://dx.doi.org/10.2147/CIA.S241936
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