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Determination of Isosorbide-5-Mononitrate in Human Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry and Its Application to a Bioequivalence Study

Isosorbide-5-mononitrate (5-ISMN), an organic nitrate vasodilator, has been widely used worldwide to prevent angina pectoris for more than two decades. A simple and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was developed and validated for the deter...

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Detalles Bibliográficos
Autores principales: Zhou, Yinping, Liu, Aijing, Jia, Ranran, Wu, Mengyi, Wu, Ni, Liu, Chunyan, Han, Zhihui, Hu, Haitang, Wang, Hongyun, He, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382726/
https://www.ncbi.nlm.nih.gov/pubmed/32724701
http://dx.doi.org/10.1155/2020/1753265

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