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High dose folic acid is a potential treatment for pulmonary hypertension, including when associated with COVID-19 pneumonia

BACKGROUND: Pulmonary hypertension is a significant complication for some patients with COVID-19 pneumonia, especially those requiring intensive care. Tachyphylaxis to the current therapy, inhaled nitric oxide (iNO), is also common. In vitro, folic acid directly increases nitric oxide (NO) productio...

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Detalles Bibliográficos
Autores principales: Wiltshire, Esko, Peña, Alexia Sophie, MacKenzie, Karen, Shaw, Geoffrey, Couper, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382921/
https://www.ncbi.nlm.nih.gov/pubmed/32759013
http://dx.doi.org/10.1016/j.mehy.2020.110142