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Thrombocytapheresis in Patient with Essential Thrombocythemia: A Case Report

Essential thrombocythemia (ET) is one of the myeloproliferative neoplasms, characterized by persistent thrombocytosis, platelets >450,000/μL, and evident clonal abnormalities like JAK2 V617F, MPL, CALR mutation and not fulfilling WHO criteria for MDS, CML, PV, and IDA. Here we report a 24-year-ol...

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Detalles Bibliográficos
Autores principales: Elhassan, Afra M., Alsaud, Arwa, Yassin, Mohamed A., Aldapt, Mahmood, Riaz, Lubna, Ghori, Firdous, Bin Ahmad, Aiman, Abdulla, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383192/
https://www.ncbi.nlm.nih.gov/pubmed/32774255
http://dx.doi.org/10.1159/000507651
Descripción
Sumario:Essential thrombocythemia (ET) is one of the myeloproliferative neoplasms, characterized by persistent thrombocytosis, platelets >450,000/μL, and evident clonal abnormalities like JAK2 V617F, MPL, CALR mutation and not fulfilling WHO criteria for MDS, CML, PV, and IDA. Here we report a 24-year-old female who presented with headache and was found to have thrombocytosis with a platelet count of 2,141 × 10(3)/μL, diagnosed as ET as per WHO criteria 2008; she required ICU admission and thrombocytapheresis with a favorable outcome.