Cohesin-Dependent and -Independent Mechanisms Mediate Chromosomal Contacts between Promoters and Enhancers

It is currently assumed that 3D chromosomal organization plays a central role in transcriptional control. However, depletion of cohesin and CTCF affects the steady-state levels of only a minority of transcripts. Here, we use high-resolution Capture Hi-C to interrogate the dynamics of chromosomal con...

Descripción completa

Detalles Bibliográficos
Autores principales: Thiecke, Michiel J., Wutz, Gordana, Muhar, Matthias, Tang, Wen, Bevan, Stephen, Malysheva, Valeriya, Stocsits, Roman, Neumann, Tobias, Zuber, Johannes, Fraser, Peter, Schoenfelder, Stefan, Peters, Jan-Michael, Spivakov, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383238/
https://www.ncbi.nlm.nih.gov/pubmed/32698000
http://dx.doi.org/10.1016/j.celrep.2020.107929

Ejemplares similares

Ejemplares similares