Cargando…

Bile Acids: Key Regulators and Novel Treatment Targets for Type 2 Diabetes

Type 2 diabetes mellitus (T2DM), characterized by insulin resistance and unclear pathogenesis, is a serious menace to human health. Bile acids are the end products of cholesterol catabolism and play an important role in maintaining cholesterol homeostasis. Furthermore, increasing studies suggest tha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yingjie, Zhou, An, Tang, Li, Lei, Yuanyuan, Tang, Bo, Zhang, Linjing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383344/ https://www.ncbi.nlm.nih.gov/pubmed/32733968 http://dx.doi.org/10.1155/2020/6138438

Ejemplares similares

Disulfiram ameliorates nonalcoholic steatohepatitis by modulating the gut microbiota and bile acid metabolism
por: Lei, Yuanyuan, et al.
Publicado: (2022)

Role of Bile Acid Sequestrants in the Treatment of Type 2 Diabetes
por: Handelsman, Yehuda
Publicado: (2011)

Myostatin Knockout Regulates Bile Acid Metabolism by Promoting Bile Acid Synthesis in Cattle
por: Wu, Di, et al.
Publicado: (2022)

Bile Acids and FXR: Novel Targets for Liver Diseases
por: Stofan, Mary, et al.
Publicado: (2020)

Identification of key genes involved in type 2 diabetic islet dysfunction: a bioinformatics study
por: Zhong, Ming, et al.
Publicado: (2019)

Dietary Bile Salt Types Influence the Composition of Biliary Bile Acids and Gut Microbiota in Grass Carp
por: Xiong, Fan, et al.
Publicado: (2018)

Spexin Acts as Novel Regulator for Bile Acid Synthesis
por: Lin, Cheng-yuan, et al.
Publicado: (2018)

Decreased Physiological Serum Total Bile Acid Concentrations in Patients with Type 2 Diabetic Peripheral Neuropathy
por: Yan, Pijun, et al.
Publicado: (2021)

Bile Acids: Key Players in Inflammatory Bowel Diseases?
por: Kriaa, Aicha, et al.
Publicado: (2022)

Gut microbiota alters host bile acid metabolism to contribute to intrahepatic cholestasis of pregnancy
por: Tang, Bo, et al.
Publicado: (2023)

Key Signaling in Alcohol-Associated Liver Disease: The Role of Bile Acids
por: Way, Grayson W., et al.
Publicado: (2022)

Serum Bile Acid Profiles in Latent Autoimmune Diabetes in Adults and Type 2 Diabetes Patients
por: Zhou, Yu, et al.
Publicado: (2022)

Bile Acid Transporters Are Expressed and Heterogeneously Distributed in Rat Bile Ducts
por: Luo, Zhu-lin, et al.
Publicado: (2019)

Targeting bile acids and lipotoxicity for NASH treatment
por: Chiang, John Y. L.
Publicado: (2017)

Effects of acids, pepsin, bile acids, and trypsin on laryngopharyngeal reflux diseases: physiopathology and therapeutic targets
por: Li, Yading, et al.
Publicado: (2021)

Bile Acids and Metabolic Regulation: Mechanisms and clinical responses to bile acid sequestration
por: Staels, Bart, et al.
Publicado: (2009)

Association between type 2 diabetes and amyotrophic lateral sclerosis
por: Zhang, Linjing, et al.
Publicado: (2022)

Association of Serum Bile Acid and Unsaturated Fatty Acid Profiles with the Risk of Diabetic Retinopathy in Type 2 Diabetic Patients
por: Feng, Susu, et al.
Publicado: (2023)

Bile acids-gut microbiota crosstalk contributes to the improvement of type 2 diabetes mellitus
por: Gao, Ruolin, et al.
Publicado: (2022)

Understanding Bile Acid Signaling in Diabetes: From Pathophysiology to Therapeutic Targets
por: Ferrell, Jessica M., et al.
Publicado: (2019)

The association between total bile acid and bone mineral density among patients with type 2 diabetes
por: Yang, Song, et al.
Publicado: (2023)

Plasma Bile Acid Profile in Patients with and without Type 2 Diabetes
por: Mantovani, Alessandro, et al.
Publicado: (2021)

Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism
por: Xu, Yanyong, et al.
Publicado: (2021)

Soaping Up Type 2 Diabetes With Bile Acids?: The Link Between Glucose and Bile Acid Metabolism in Humans Tightens: Quality Matters!
por: Staels, Bart, et al.
Publicado: (2013)

Colon cancer checks in when bile acids check out: the bile acid–nuclear receptor axis in colon cancer
por: Tang, Qin, et al.
Publicado: (2021)

Endoplasmic Reticulum Stress Emerges as Novel Regulator for Bile Acid Synthesis
por: Guo, Grace
Publicado: (2017)

Research progress on the relationship between bile acid metabolism and type 2 diabetes mellitus
por: Hou, Yisen, et al.
Publicado: (2023)

The relationship between bile acid concentration, glucagon-like-peptide 1, fibroblast growth factor 15 and bile acid receptors in rats during progression of glucose intolerance
por: Yan, Xinfeng, et al.
Publicado: (2017)

Regulation of bile acid receptor activity(☆)
por: Wan, Yu-Jui Yvonne, et al.
Publicado: (2018)

Novel nitroxide-bile acid conjugates inform substrate requirements for human bile acid transporters
por: Metry, Melissa, et al.
Publicado: (2023)

Serum metabolome and targeted bile acid profiling reveals potential novel biomarkers for drug-induced liver injury
por: Ma, Zhenhua, et al.
Publicado: (2019)

Hepatokines, bile acids and ketone bodies are novel Hormones regulating energy homeostasis
por: Garruti, Gabriella, et al.
Publicado: (2023)

Bile Acids as Key Modulators of the Brain-Gut-Microbiota Axis in Alzheimer’s Disease
por: Mulak, Agata
Publicado: (2021)

Bile acids and their receptors: Potential therapeutic targets in inflammatory bowel disease
por: Long, Xiong-Quan, et al.
Publicado: (2023)

Regulation of Bile Acid and Cholesterol Metabolism by PPARs
por: Li, Tiangang, et al.
Publicado: (2009)

Bile Acids: Major Regulator of the Gut Microbiome
por: An, Chihyeok, et al.
Publicado: (2022)

Rebuttal to: The Benevolent Bile: Bile Acids as Stimulants of Liver Regeneration
por: Zhou, Weinan, et al.
Publicado: (2022)

The Effect of a Bile Acid Sequestrant on Glucose Metabolism in Subjects With Type 2 Diabetes
por: Smushkin, Galina, et al.
Publicado: (2013)

Dysregulation of secondary bile acid metabolism precedes islet autoimmunity and type 1 diabetes
por: Lamichhane, Santosh, et al.
Publicado: (2022)

Elevated First-Trimester Total Bile Acid is Associated with the Risk of Subsequent Gestational Diabetes
por: Hou, Wolin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_lkjtvgntc8lsb8og9blcoofe26