MiR‐1253 exerts tumor‐suppressive effects in medulloblastoma via inhibition of CDK6 and CD276 (B7‐H3)

Of the four primary subgroups of medulloblastoma, the most frequent cytogenetic abnormality, i17q, distinguishes Groups 3 and 4 which carry the highest mortality; haploinsufficiency of 17p13.3 is a marker for particularly poor prognosis. At the terminal end of this locus lies miR‐1253, a brain‐enric...

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Detalles Bibliográficos
Autores principales: Kanchan, Ranjana K., Perumal, Naveenkumar, Atri, Pranita, Chirravuri Venkata, Ramakanth, Thapa, Ishwor, Klinkebiel, David L., Donson, Andrew M., Perry, Deborah, Punsoni, Michael, Talmon, Geoffrey A., Coulter, Donald W., Boue’, Daniel R., Snuderl, Matija, Nasser, Mohd. W., Batra, Surinder K., Vibhakar, Rajeev, Mahapatra, Sidharth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383594/
https://www.ncbi.nlm.nih.gov/pubmed/32145124
http://dx.doi.org/10.1111/bpa.12829

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