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Ablation of reactive astrocytes exacerbates disease pathology in a model of Alzheimer's disease

The role of astrocytes in the progression of Alzheimer's disease (AD) remains poorly understood. We assessed the consequences of ablating astrocytic proliferation in 9 months old double transgenic APP23/GFAP‐TK mice. Treatment of these mice with the antiviral agent ganciclovir conditionally abl...

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Detalles Bibliográficos
Autores principales:	Katsouri, Loukia, Birch, Amy M., Renziehausen, Alexander W. J., Zach, Carolin, Aman, Yahyah, Steeds, Hannah, Bonsu, Angela, Palmer, Emily O. C., Mirzaei, Nazanin, Ries, Miriam, Sastre, Magdalena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383629/ https://www.ncbi.nlm.nih.gov/pubmed/31799735 http://dx.doi.org/10.1002/glia.23759

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