Cargando…
Threshold dynamics of a time-delayed epidemic model for continuous imperfect-vaccine with a generalized nonmonotone incidence rate
In this paper, we study the dynamics of an infectious disease in the presence of a continuous-imperfect vaccine and latent period. We consider a general incidence rate function with a non-monotonicity property to interpret the psychological effect in the susceptible population. After we propose the...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383700/ https://www.ncbi.nlm.nih.gov/pubmed/32836815 http://dx.doi.org/10.1007/s11071-020-05825-x |
Sumario: | In this paper, we study the dynamics of an infectious disease in the presence of a continuous-imperfect vaccine and latent period. We consider a general incidence rate function with a non-monotonicity property to interpret the psychological effect in the susceptible population. After we propose the model, we provide the well-posedness property and calculate the effective reproduction number [Formula: see text] . Then, we obtain the threshold dynamics of the system with respect to [Formula: see text] by studying the global stability of the disease-free equilibrium when [Formula: see text] and the system persistence when [Formula: see text] . For the endemic equilibrium, we use the semi-discretization method to analyze its linear stability. Then, we discuss the critical vaccination coverage rate that is required to eliminate the disease. Numerical simulations are provided to implement a case study regarding data of influenza patients, study the local and global sensitivity of [Formula: see text] , construct approximate stability charts for the endemic equilibrium over different parameter spaces and explore the sensitivity of the proposed model solutions. |
---|