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Bactericidal Activity Study of ZrO(2)-Ag(2)O Nanoparticles

In view of the continuous resistance to antibacterial agents by bacteria and the existing problems of silver nanoparticles as an antibacterial agent, this study reports on the synthesis of pure zirconium oxide, silver oxide, and ZrO(2)-Ag(2)O nanoparticles by sol-gel method. The nanoparticles were a...

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Autores principales: Ayanwale, Ayodeji Precious, Ruíz-Baltazar, Alvaro de Jesús, Espinoza-Cristóbal, León, Reyes-López, Simón Yobanny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383718/
https://www.ncbi.nlm.nih.gov/pubmed/32782447
http://dx.doi.org/10.1177/1559325820941374
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author Ayanwale, Ayodeji Precious
Ruíz-Baltazar, Alvaro de Jesús
Espinoza-Cristóbal, León
Reyes-López, Simón Yobanny
author_facet Ayanwale, Ayodeji Precious
Ruíz-Baltazar, Alvaro de Jesús
Espinoza-Cristóbal, León
Reyes-López, Simón Yobanny
author_sort Ayanwale, Ayodeji Precious
collection PubMed
description In view of the continuous resistance to antibacterial agents by bacteria and the existing problems of silver nanoparticles as an antibacterial agent, this study reports on the synthesis of pure zirconium oxide, silver oxide, and ZrO(2)-Ag(2)O nanoparticles by sol-gel method. The nanoparticles were analyzed and tested for their antibacterial activity against gram-positive bacteria of Bacillus subtilis, Streptococcus mutans, Staphylococcus aureus, and gram-negative of Escherichia coli, Pseudomonas aeruginosa, and Klebsiella oxytoca. X-ray diffraction showed the monoclinic ZrO(2), cubic Ag(2)O, and peaks corresponding to ZrO(2) and Ag(2)O in their mixed samples. Scanning electron microscopy showed spherically shaped nanoparticles while dynamic light scattering analysis showed ZrO(2) (76 nm), Ag(2)O (50 nm), and ZrO(2)-Ag(2)O samples between 14 and 42 nm. The Fourier Transformed Infrared spectroscopy spectra of ZrO(2) gave bands at 480 cm(−1) to 750 cm(−1) (M-O stretching) with Ag(2)O at 580 cm(−1), while ZrO(2)-Ag(2)O samples showed bands at 760 cm(−1). The screening by agar diffusion assay revealed a pronounced increase in the antibacterial activity of ZrO(2)-Ag(2)O against all the tested bacteria when compared with the pure ZrO(2) and Ag(2)O. The improved antibacterial activity of ZrO(2)-Ag(2)O largely results from the chemical stability conferred on it by the ZrO(2) as observed from the zeta potential measurement.
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spelling pubmed-73837182020-08-10 Bactericidal Activity Study of ZrO(2)-Ag(2)O Nanoparticles Ayanwale, Ayodeji Precious Ruíz-Baltazar, Alvaro de Jesús Espinoza-Cristóbal, León Reyes-López, Simón Yobanny Dose Response Nanotechnology and Microtechnology in Drug Delivery System In view of the continuous resistance to antibacterial agents by bacteria and the existing problems of silver nanoparticles as an antibacterial agent, this study reports on the synthesis of pure zirconium oxide, silver oxide, and ZrO(2)-Ag(2)O nanoparticles by sol-gel method. The nanoparticles were analyzed and tested for their antibacterial activity against gram-positive bacteria of Bacillus subtilis, Streptococcus mutans, Staphylococcus aureus, and gram-negative of Escherichia coli, Pseudomonas aeruginosa, and Klebsiella oxytoca. X-ray diffraction showed the monoclinic ZrO(2), cubic Ag(2)O, and peaks corresponding to ZrO(2) and Ag(2)O in their mixed samples. Scanning electron microscopy showed spherically shaped nanoparticles while dynamic light scattering analysis showed ZrO(2) (76 nm), Ag(2)O (50 nm), and ZrO(2)-Ag(2)O samples between 14 and 42 nm. The Fourier Transformed Infrared spectroscopy spectra of ZrO(2) gave bands at 480 cm(−1) to 750 cm(−1) (M-O stretching) with Ag(2)O at 580 cm(−1), while ZrO(2)-Ag(2)O samples showed bands at 760 cm(−1). The screening by agar diffusion assay revealed a pronounced increase in the antibacterial activity of ZrO(2)-Ag(2)O against all the tested bacteria when compared with the pure ZrO(2) and Ag(2)O. The improved antibacterial activity of ZrO(2)-Ag(2)O largely results from the chemical stability conferred on it by the ZrO(2) as observed from the zeta potential measurement. SAGE Publications 2020-07-24 /pmc/articles/PMC7383718/ /pubmed/32782447 http://dx.doi.org/10.1177/1559325820941374 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Nanotechnology and Microtechnology in Drug Delivery System
Ayanwale, Ayodeji Precious
Ruíz-Baltazar, Alvaro de Jesús
Espinoza-Cristóbal, León
Reyes-López, Simón Yobanny
Bactericidal Activity Study of ZrO(2)-Ag(2)O Nanoparticles
title Bactericidal Activity Study of ZrO(2)-Ag(2)O Nanoparticles
title_full Bactericidal Activity Study of ZrO(2)-Ag(2)O Nanoparticles
title_fullStr Bactericidal Activity Study of ZrO(2)-Ag(2)O Nanoparticles
title_full_unstemmed Bactericidal Activity Study of ZrO(2)-Ag(2)O Nanoparticles
title_short Bactericidal Activity Study of ZrO(2)-Ag(2)O Nanoparticles
title_sort bactericidal activity study of zro(2)-ag(2)o nanoparticles
topic Nanotechnology and Microtechnology in Drug Delivery System
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383718/
https://www.ncbi.nlm.nih.gov/pubmed/32782447
http://dx.doi.org/10.1177/1559325820941374
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