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Allergen alters IL‐2/αIL‐2‐based Treg expansion but not tolerance induction in an allergen‐specific mouse model
BACKGROUND: Regulatory T lymphocytes (Treg) play an important role in preventing allergic diseases. We characterized Treg expansion kinetics, marker profiles, and recirculation behavior in allergen‐challenged mice, which had been pretreated with IL‐2/αIL‐2 complexes in the presence or absence of all...
Autores principales: | Köhler, Cordula, Smole, Ursula, Kratzer, Bernhard, Trapin, Doris, Schmetterer, Klaus G., Pickl, Winfried F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383865/ https://www.ncbi.nlm.nih.gov/pubmed/31991489 http://dx.doi.org/10.1111/all.14203 |
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