Cargando…

Label‐Free Nanoimaging of Neuromelanin in the Brain by Soft X‐ray Spectromicroscopy

A hallmark of Parkinson's disease is the death of neuromelanin‐pigmented neurons, but the role of neuromelanin is unclear. The in situ characterization of neuromelanin remains dependent on detectable pigmentation, rather than direct quantification of neuromelanin. We show that direct, label‐fre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brooks, Jake, Everett, James, Lermyte, Frederik, Tjhin, Vindy Tjendana, Banerjee, Samya, O'Connor, Peter B., Morris, Christopher M., Sadler, Peter J., Telling, Neil D., Collingwood, Joanna F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383895/ https://www.ncbi.nlm.nih.gov/pubmed/32227670 http://dx.doi.org/10.1002/anie.202000239

Ejemplares similares

Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects
por: Everett, James, et al.
Publicado: (2018)

Biogenic metallic elements in the human brain?
por: Everett, James, et al.
Publicado: (2021)

Iron stored in ferritin is chemically reduced in the presence of aggregating Aβ(1-42)
por: Everett, James, et al.
Publicado: (2020)

Emerging Approaches to Investigate the Influence of Transition Metals in the Proteinopathies
por: Lermyte, Frederik, et al.
Publicado: (2019)

Impact of Autophagy and Aging on Iron Load and Ferritin in Drosophila Brain
por: Jacomin, Anne-Claire, et al.
Publicado: (2019)

Metal Ion Binding to the Amyloid β Monomer Studied by Native Top-Down FTICR Mass Spectrometry
por: Lermyte, Frederik, et al.
Publicado: (2019)

Characterization of Biomaterials by Soft X-Ray Spectromicroscopy
por: Leung, Bonnie O., et al.
Publicado: (2010)

Oral Administration of Lipopolysaccharide Enhances Insulin Signaling-Related Factors in the KK/Ay Mouse Model of Type 2 Diabetes Mellitus
por: Yamamoto, Kazushi, et al.
Publicado: (2023)

Soft x-ray spectromicroscopy and its application to semiconductor microstructure characterization
por: Gozzo, F, et al.
Publicado: (1996)

In Situ Soft X-ray Spectromicroscopy of Early Tricalcium Silicate Hydration
por: Bae, Sungchul, et al.
Publicado: (2016)

Introduction of Soft X-Ray Spectromicroscopy as an Advanced Technique for Plant Biopolymers Research
por: Karunakaran, Chithra, et al.
Publicado: (2015)

Chemical and elemental mapping of spent nuclear fuel sections by soft X-ray spectromicroscopy
por: Ditter, Alexander Scott, et al.
Publicado: (2022)

Infrared vibrational nanocrystallography and nanoimaging
por: Muller, Eric A., et al.
Publicado: (2016)

Nanoimaging granule dynamics and subcellular structures in activated mast cells using soft X-ray tomography
por: Chen, Huan-Yuan, et al.
Publicado: (2016)

Upscaling X-ray nanoimaging to macroscopic specimens
por: Du, Ming, et al.
Publicado: (2021)

Facile protein conjugation of platinum for light-activated cytotoxic payload release
por: Imberti, Cinzia, et al.
Publicado: (2021)

Corrigendum: Nanoimaging granule dynamics and subcellular structures in activated mast cells using soft X-ray tomography
por: Chen, Huan-Yuan, et al.
Publicado: (2017)

Spatially resolved TiO(x) phases in switched RRAM devices using soft X-ray spectromicroscopy
por: Carta, D., et al.
Publicado: (2016)

Cathode lens spectromicroscopy: methodology and applications
por: Menteş, T O, et al.
Publicado: (2014)

Quantitative material analysis using secondary electron energy spectromicroscopy
por: Han, W., et al.
Publicado: (2020)

Chemical-state distributions in charged LiCoO(2) cathode particles visualized by soft X-ray spectromicroscopy
por: Zhang, Wenxiong, et al.
Publicado: (2023)

Synthetic optical holography for rapid nanoimaging
por: Schnell, M., et al.
Publicado: (2014)

White nanolight source for optical nanoimaging
por: Umakoshi, Takayuki, et al.
Publicado: (2020)

Multimodal X-ray nano-spectromicroscopy analysis of chemically heterogeneous systems
por: Pattammattel, Ajith, et al.
Publicado: (2022)

Counting on the future: fast charge-integrating detectors for X-ray nanoimaging
por: Deng, Junjing, et al.
Publicado: (2023)

Status Report from the Fifth International Conference on X-Ray Microscopy and Spectromicroscopy
por: Thieme, Jürgen, et al.
Publicado: (1998)

Nanoimaging of Focal Adhesion Dynamics in 3D
por: Chiu, Chi-Li, et al.
Publicado: (2014)

Nanoimaging in cardiovascular diseases: Current state of the art
por: Deb, Suryyani, et al.
Publicado: (2015)

Bacterial cell wall nanoimaging by autoblinking microscopy
por: Floc’h, Kevin, et al.
Publicado: (2018)

Visualization of elemental distributions and local analysis of element-specific chemical states of an Arachnoidiscus sp. frustule using soft X-ray spectromicroscopy
por: Ishihara, Tomoko, et al.
Publicado: (2020)

Author Correction: Quantitative material analysis using secondary electron energy spectromicroscopy
por: Han, W., et al.
Publicado: (2021)

The role of tyrosine hydroxylase as a key player in neuromelanin synthesis and the association of neuromelanin with Parkinson’s disease
por: Nagatsu, Toshiharu, et al.
Publicado: (2023)

Nanomechanical Photothermal Near Infrared Spectromicroscopy of Individual Nanorods
por: Kanellopulos, Kostas, et al.
Publicado: (2023)

MAXPEEM: a spectromicroscopy beamline at MAX IV laboratory
por: Niu, Yuran, et al.
Publicado: (2023)

Nanoimaging for Molecular Pharmaceutics of Alzheimer’s and other Neurodegenerative Disorders
por: Lyubchenko, Yuri L
Publicado: (2013)

Effects of edge on graphene plasmons as revealed by infrared nanoimaging
por: Xu, Qingyang, et al.
Publicado: (2017)

Vibrational exciton nanoimaging of phases and domains in porphyrin nanocrystals
por: Muller, Eric A., et al.
Publicado: (2020)

4D nanoimaging of early age cement hydration
por: Shirani, Shiva, et al.
Publicado: (2023)

Three-dimensional nanoimaging of fuel cell catalyst layers
por: Girod, Robin, et al.
Publicado: (2023)

First results from the spectromicroscopy beamline at the Advanced Light Source
por: Denlinger, J D, et al.
Publicado: (1995)

Cannot write session to /tmp/vufind_sessions/sess_oq4p3j3l2e0o0k656jq9ilod8o