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Synthesis of Novel Pyridine‐Carboxylates as Small‐Molecule Inhibitors of Human Aspartate/Asparagine‐β‐Hydroxylase

The human 2‐oxoglutarate (2OG)‐dependent oxygenase aspartate/asparagine‐β‐hydroxylase (AspH) is a potential medicinal chemistry target for anticancer therapy. AspH is present on the cell surface of invasive cancer cells and accepts epidermal growth factor‐like domain (EGFD) substrates with a noncano...

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Detalles Bibliográficos
Autores principales:	Brewitz, Lennart, Tumber, Anthony, Thalhammer, Armin, Salah, Eidarus, Christensen, Kirsten E., Schofield, Christopher J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383925/ https://www.ncbi.nlm.nih.gov/pubmed/32330361 http://dx.doi.org/10.1002/cmdc.202000147

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