CD8(+) T Cell Functional Exhaustion Overrides Pregnancy-Induced Fetal Antigen Alloimmunization

Pregnancy necessitates physiological exposure, and often re-exposure, to foreign fetal alloantigens. The consequences after pregnancy are highly varied, with evidence of both alloimmunization and expanded tolerance phenotypes. We show that pregnancy primes the accumulation of fetal-specific maternal...

Descripción completa

Detalles Bibliográficos
Autores principales: Kinder, Jeremy M., Turner, Lucien H., Stelzer, Ina A., Miller-Handley, Hilary, Burg, Ashley, Shao, Tzu-Yu, Pham, Giang, Way, Sing Sing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383938/
https://www.ncbi.nlm.nih.gov/pubmed/32579916
http://dx.doi.org/10.1016/j.celrep.2020.107784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7383938/
https://www.ncbi.nlm.nih.gov/pubmed/32579916
http://dx.doi.org/10.1016/j.celrep.2020.107784

Ejemplares similares