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π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation

Free base, zinc and palladium π‐extended porphyrins containing fused naphthalenediamide units were employed as photosensitizers in antimicrobial photodynamic therapy (aPDT). Their efficacy, assessed by photophysical and in vitro photobiological studies on Gram‐positive bacteria, was found to depend...

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Autores principales: Galstyan, Anzhela, Maurya, Yogesh Kumar, Zhylitskaya, Halina, Bae, Youn Jue, Wu, Yi‐Lin, Wasielewski, Michael R., Lis, Tadeusz, Dobrindt, Ulrich, Stępień, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384002/
https://www.ncbi.nlm.nih.gov/pubmed/31968144
http://dx.doi.org/10.1002/chem.201905372
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author Galstyan, Anzhela
Maurya, Yogesh Kumar
Zhylitskaya, Halina
Bae, Youn Jue
Wu, Yi‐Lin
Wasielewski, Michael R.
Lis, Tadeusz
Dobrindt, Ulrich
Stępień, Marcin
author_facet Galstyan, Anzhela
Maurya, Yogesh Kumar
Zhylitskaya, Halina
Bae, Youn Jue
Wu, Yi‐Lin
Wasielewski, Michael R.
Lis, Tadeusz
Dobrindt, Ulrich
Stępień, Marcin
author_sort Galstyan, Anzhela
collection PubMed
description Free base, zinc and palladium π‐extended porphyrins containing fused naphthalenediamide units were employed as photosensitizers in antimicrobial photodynamic therapy (aPDT). Their efficacy, assessed by photophysical and in vitro photobiological studies on Gram‐positive bacteria, was found to depend on metal coordination, showing a dramatic enhancement of photosensitizing activity for the palladium complex.
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spelling pubmed-73840022020-07-28 π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation Galstyan, Anzhela Maurya, Yogesh Kumar Zhylitskaya, Halina Bae, Youn Jue Wu, Yi‐Lin Wasielewski, Michael R. Lis, Tadeusz Dobrindt, Ulrich Stępień, Marcin Chemistry Full Papers Free base, zinc and palladium π‐extended porphyrins containing fused naphthalenediamide units were employed as photosensitizers in antimicrobial photodynamic therapy (aPDT). Their efficacy, assessed by photophysical and in vitro photobiological studies on Gram‐positive bacteria, was found to depend on metal coordination, showing a dramatic enhancement of photosensitizing activity for the palladium complex. John Wiley and Sons Inc. 2020-06-08 2020-07-02 /pmc/articles/PMC7384002/ /pubmed/31968144 http://dx.doi.org/10.1002/chem.201905372 Text en © 2020 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Full Papers
Galstyan, Anzhela
Maurya, Yogesh Kumar
Zhylitskaya, Halina
Bae, Youn Jue
Wu, Yi‐Lin
Wasielewski, Michael R.
Lis, Tadeusz
Dobrindt, Ulrich
Stępień, Marcin
π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation
title π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation
title_full π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation
title_fullStr π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation
title_full_unstemmed π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation
title_short π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation
title_sort π‐extended donor–acceptor porphyrins and metalloporphyrins for antimicrobial photodynamic inactivation
topic Full Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384002/
https://www.ncbi.nlm.nih.gov/pubmed/31968144
http://dx.doi.org/10.1002/chem.201905372
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