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π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation
Free base, zinc and palladium π‐extended porphyrins containing fused naphthalenediamide units were employed as photosensitizers in antimicrobial photodynamic therapy (aPDT). Their efficacy, assessed by photophysical and in vitro photobiological studies on Gram‐positive bacteria, was found to depend...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384002/ https://www.ncbi.nlm.nih.gov/pubmed/31968144 http://dx.doi.org/10.1002/chem.201905372 |
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author | Galstyan, Anzhela Maurya, Yogesh Kumar Zhylitskaya, Halina Bae, Youn Jue Wu, Yi‐Lin Wasielewski, Michael R. Lis, Tadeusz Dobrindt, Ulrich Stępień, Marcin |
author_facet | Galstyan, Anzhela Maurya, Yogesh Kumar Zhylitskaya, Halina Bae, Youn Jue Wu, Yi‐Lin Wasielewski, Michael R. Lis, Tadeusz Dobrindt, Ulrich Stępień, Marcin |
author_sort | Galstyan, Anzhela |
collection | PubMed |
description | Free base, zinc and palladium π‐extended porphyrins containing fused naphthalenediamide units were employed as photosensitizers in antimicrobial photodynamic therapy (aPDT). Their efficacy, assessed by photophysical and in vitro photobiological studies on Gram‐positive bacteria, was found to depend on metal coordination, showing a dramatic enhancement of photosensitizing activity for the palladium complex. |
format | Online Article Text |
id | pubmed-7384002 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73840022020-07-28 π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation Galstyan, Anzhela Maurya, Yogesh Kumar Zhylitskaya, Halina Bae, Youn Jue Wu, Yi‐Lin Wasielewski, Michael R. Lis, Tadeusz Dobrindt, Ulrich Stępień, Marcin Chemistry Full Papers Free base, zinc and palladium π‐extended porphyrins containing fused naphthalenediamide units were employed as photosensitizers in antimicrobial photodynamic therapy (aPDT). Their efficacy, assessed by photophysical and in vitro photobiological studies on Gram‐positive bacteria, was found to depend on metal coordination, showing a dramatic enhancement of photosensitizing activity for the palladium complex. John Wiley and Sons Inc. 2020-06-08 2020-07-02 /pmc/articles/PMC7384002/ /pubmed/31968144 http://dx.doi.org/10.1002/chem.201905372 Text en © 2020 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Full Papers Galstyan, Anzhela Maurya, Yogesh Kumar Zhylitskaya, Halina Bae, Youn Jue Wu, Yi‐Lin Wasielewski, Michael R. Lis, Tadeusz Dobrindt, Ulrich Stępień, Marcin π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation |
title | π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation |
title_full | π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation |
title_fullStr | π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation |
title_full_unstemmed | π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation |
title_short | π‐Extended Donor–Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation |
title_sort | π‐extended donor–acceptor porphyrins and metalloporphyrins for antimicrobial photodynamic inactivation |
topic | Full Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384002/ https://www.ncbi.nlm.nih.gov/pubmed/31968144 http://dx.doi.org/10.1002/chem.201905372 |
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