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Germs and germlines: how “public” B‐cell clones evolve in the gut

Chen et al. describe how B‐cell clones observed in the gut of many different individuals (recurrent or “public” clonotypes) are shaped by the combined influences of common microbial antigens and underlying genomic recombination biases.[Image: see text]

Detalles Bibliográficos
Autores principales: James, Kylie R, King, Hamish W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384023/
https://www.ncbi.nlm.nih.gov/pubmed/32418276
http://dx.doi.org/10.1111/imcb.12340
Descripción
Sumario:Chen et al. describe how B‐cell clones observed in the gut of many different individuals (recurrent or “public” clonotypes) are shaped by the combined influences of common microbial antigens and underlying genomic recombination biases.[Image: see text]