Spectrum of PALB2 germline mutations and characteristics of PALB2‐related breast cancer: Screening of 16,501 unselected patients with breast cancer and 5890 controls by next‐generation sequencing

BACKGROUND: Partner and localizer BRCA2 (PALB2) is a breast cancer predisposition gene, but the clinical relevance of PALB2 germline mutations in Chinese patients with breast cancer remains unknown. This study attempted to investigate the full prevalence and spectrum of PALB2 germline mutations in C...

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Detalles Bibliográficos
Autores principales: Zhou, Jiaojiao, Wang, Honglian, Fu, Fangmeng, Li, Zhanwen, Feng, Qingjian, Wu, Weizhu, Liu, Yun, Wang, Chuan, Chen, Yiding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384117/
https://www.ncbi.nlm.nih.gov/pubmed/32339256
http://dx.doi.org/10.1002/cncr.32905

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