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Constitutive activity of a G protein‐coupled receptor, DRD1, contributes to human cerebral organoid formation

The intricate balance of neural stem cell (NSC) amplification and neurogenesis is central to nervous system development. Dopamine D1 receptor (DRD1) is a typical G protein‐coupled receptor (GPCR) mainly expressed in neurogenic area, with high constitutive activity. The receptor appears in the embryo...

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Detalles Bibliográficos
Autores principales:	Wang, Qinying, Dong, Xiaoxu, Lu, Jing, Hu, Tingting, Pei, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2020
Materias:	Stem Cell Technology: Epigenetics, Genomics, Proteomics and Metabonomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384186/ https://www.ncbi.nlm.nih.gov/pubmed/32052915 http://dx.doi.org/10.1002/stem.3156

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