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An insight on medicinal attributes of 1,2,4-triazoles
The present review aims to summarize the pharmacological profile of 1,2,4-triazole, one of the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant, antituberculosis, antiviral, antiparasitic, analgesic and anti-inflammatory agents, etc. along with structure-activit...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Masson SAS.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384432/ https://www.ncbi.nlm.nih.gov/pubmed/32771798 http://dx.doi.org/10.1016/j.ejmech.2020.112652 |
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author | Aggarwal, Ranjana Sumran, Garima |
author_facet | Aggarwal, Ranjana Sumran, Garima |
author_sort | Aggarwal, Ranjana |
collection | PubMed |
description | The present review aims to summarize the pharmacological profile of 1,2,4-triazole, one of the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant, antituberculosis, antiviral, antiparasitic, analgesic and anti-inflammatory agents, etc. along with structure-activity relationship. The comprehensive compilation of work carried out in the last decade on 1,2,4-triazole nucleus will provide inevitable scope for researchers for the advancement of novel potential drug candidates having better efficacy and selectivity. |
format | Online Article Text |
id | pubmed-7384432 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier Masson SAS. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73844322020-07-28 An insight on medicinal attributes of 1,2,4-triazoles Aggarwal, Ranjana Sumran, Garima Eur J Med Chem Review Article The present review aims to summarize the pharmacological profile of 1,2,4-triazole, one of the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant, antituberculosis, antiviral, antiparasitic, analgesic and anti-inflammatory agents, etc. along with structure-activity relationship. The comprehensive compilation of work carried out in the last decade on 1,2,4-triazole nucleus will provide inevitable scope for researchers for the advancement of novel potential drug candidates having better efficacy and selectivity. Elsevier Masson SAS. 2020-11-01 2020-07-27 /pmc/articles/PMC7384432/ /pubmed/32771798 http://dx.doi.org/10.1016/j.ejmech.2020.112652 Text en © 2020 Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Review Article Aggarwal, Ranjana Sumran, Garima An insight on medicinal attributes of 1,2,4-triazoles |
title | An insight on medicinal attributes of 1,2,4-triazoles |
title_full | An insight on medicinal attributes of 1,2,4-triazoles |
title_fullStr | An insight on medicinal attributes of 1,2,4-triazoles |
title_full_unstemmed | An insight on medicinal attributes of 1,2,4-triazoles |
title_short | An insight on medicinal attributes of 1,2,4-triazoles |
title_sort | insight on medicinal attributes of 1,2,4-triazoles |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384432/ https://www.ncbi.nlm.nih.gov/pubmed/32771798 http://dx.doi.org/10.1016/j.ejmech.2020.112652 |
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