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An insight on medicinal attributes of 1,2,4-triazoles

The present review aims to summarize the pharmacological profile of 1,2,4-triazole, one of the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant, antituberculosis, antiviral, antiparasitic, analgesic and anti-inflammatory agents, etc. along with structure-activit...

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Detalles Bibliográficos
Autores principales: Aggarwal, Ranjana, Sumran, Garima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384432/
https://www.ncbi.nlm.nih.gov/pubmed/32771798
http://dx.doi.org/10.1016/j.ejmech.2020.112652
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author Aggarwal, Ranjana
Sumran, Garima
author_facet Aggarwal, Ranjana
Sumran, Garima
author_sort Aggarwal, Ranjana
collection PubMed
description The present review aims to summarize the pharmacological profile of 1,2,4-triazole, one of the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant, antituberculosis, antiviral, antiparasitic, analgesic and anti-inflammatory agents, etc. along with structure-activity relationship. The comprehensive compilation of work carried out in the last decade on 1,2,4-triazole nucleus will provide inevitable scope for researchers for the advancement of novel potential drug candidates having better efficacy and selectivity.
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spelling pubmed-73844322020-07-28 An insight on medicinal attributes of 1,2,4-triazoles Aggarwal, Ranjana Sumran, Garima Eur J Med Chem Review Article The present review aims to summarize the pharmacological profile of 1,2,4-triazole, one of the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant, antituberculosis, antiviral, antiparasitic, analgesic and anti-inflammatory agents, etc. along with structure-activity relationship. The comprehensive compilation of work carried out in the last decade on 1,2,4-triazole nucleus will provide inevitable scope for researchers for the advancement of novel potential drug candidates having better efficacy and selectivity. Elsevier Masson SAS. 2020-11-01 2020-07-27 /pmc/articles/PMC7384432/ /pubmed/32771798 http://dx.doi.org/10.1016/j.ejmech.2020.112652 Text en © 2020 Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review Article
Aggarwal, Ranjana
Sumran, Garima
An insight on medicinal attributes of 1,2,4-triazoles
title An insight on medicinal attributes of 1,2,4-triazoles
title_full An insight on medicinal attributes of 1,2,4-triazoles
title_fullStr An insight on medicinal attributes of 1,2,4-triazoles
title_full_unstemmed An insight on medicinal attributes of 1,2,4-triazoles
title_short An insight on medicinal attributes of 1,2,4-triazoles
title_sort insight on medicinal attributes of 1,2,4-triazoles
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384432/
https://www.ncbi.nlm.nih.gov/pubmed/32771798
http://dx.doi.org/10.1016/j.ejmech.2020.112652
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