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Carcinosarcoma of the Mediastinum: A Rare Cause of Vocal Cord Palsy and Progressive Dysphagia

Carcinosarcoma is a rare type of malignant tumour that possess both the elements of carcinoma and sarcoma. They may occur in various locations such as the uterus, breast, thyroid, lung and gastrointestinal system. However, very few primary mediastinal carcinosarcomas have been reported. We are prese...

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Autores principales: Kanesan, Nithya, Mohamad, Irfan, Mohamad Umbaik, Norsyamira Aida, Zawawi, Norzaliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Istanbul Medeniyet University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384507/
https://www.ncbi.nlm.nih.gov/pubmed/32733767
http://dx.doi.org/10.5222/MMJ.2020.82956
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author Kanesan, Nithya
Mohamad, Irfan
Mohamad Umbaik, Norsyamira Aida
Zawawi, Norzaliana
author_facet Kanesan, Nithya
Mohamad, Irfan
Mohamad Umbaik, Norsyamira Aida
Zawawi, Norzaliana
author_sort Kanesan, Nithya
collection PubMed
description Carcinosarcoma is a rare type of malignant tumour that possess both the elements of carcinoma and sarcoma. They may occur in various locations such as the uterus, breast, thyroid, lung and gastrointestinal system. However, very few primary mediastinal carcinosarcomas have been reported. We are presenting a case of a 75-year-old male who presented with progressive dysphagia and hoarseness for 3 weeks. Contrast-enhanced computed tomography of the neck showed features of enlarged mediastinal necrotic nodes and the biopsy of this mass showed morphology and immunohistochemical profile that are consistent with carcinosarcoma. However, the patient succumbed to his illness soon after diagnosis.
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spelling pubmed-73845072020-07-29 Carcinosarcoma of the Mediastinum: A Rare Cause of Vocal Cord Palsy and Progressive Dysphagia Kanesan, Nithya Mohamad, Irfan Mohamad Umbaik, Norsyamira Aida Zawawi, Norzaliana Medeni Med J Case Report Carcinosarcoma is a rare type of malignant tumour that possess both the elements of carcinoma and sarcoma. They may occur in various locations such as the uterus, breast, thyroid, lung and gastrointestinal system. However, very few primary mediastinal carcinosarcomas have been reported. We are presenting a case of a 75-year-old male who presented with progressive dysphagia and hoarseness for 3 weeks. Contrast-enhanced computed tomography of the neck showed features of enlarged mediastinal necrotic nodes and the biopsy of this mass showed morphology and immunohistochemical profile that are consistent with carcinosarcoma. However, the patient succumbed to his illness soon after diagnosis. Istanbul Medeniyet University 2020 2020-06-30 /pmc/articles/PMC7384507/ /pubmed/32733767 http://dx.doi.org/10.5222/MMJ.2020.82956 Text en Copyright Istanbul Medeniyet University Faculty of Medicine. http://creativecommons.org/licenses/by-nc/4.0/ This journal is published by Logos Medical Publishing. Licenced by Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
spellingShingle Case Report
Kanesan, Nithya
Mohamad, Irfan
Mohamad Umbaik, Norsyamira Aida
Zawawi, Norzaliana
Carcinosarcoma of the Mediastinum: A Rare Cause of Vocal Cord Palsy and Progressive Dysphagia
title Carcinosarcoma of the Mediastinum: A Rare Cause of Vocal Cord Palsy and Progressive Dysphagia
title_full Carcinosarcoma of the Mediastinum: A Rare Cause of Vocal Cord Palsy and Progressive Dysphagia
title_fullStr Carcinosarcoma of the Mediastinum: A Rare Cause of Vocal Cord Palsy and Progressive Dysphagia
title_full_unstemmed Carcinosarcoma of the Mediastinum: A Rare Cause of Vocal Cord Palsy and Progressive Dysphagia
title_short Carcinosarcoma of the Mediastinum: A Rare Cause of Vocal Cord Palsy and Progressive Dysphagia
title_sort carcinosarcoma of the mediastinum: a rare cause of vocal cord palsy and progressive dysphagia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384507/
https://www.ncbi.nlm.nih.gov/pubmed/32733767
http://dx.doi.org/10.5222/MMJ.2020.82956
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