The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence

Aspergillus fumigatus is an opportunistic fungal pathogen that secretes an array of immune-modulatory molecules, including secondary metabolites (SMs), which contribute to enhancing fungal fitness and growth within the mammalian host. Gliotoxin (GT) is a SM that interferes with the function and recr...

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Detalles Bibliográficos
Autores principales: Ries, Laure N. A., Pardeshi, Lakhansing, Dong, Zhiqiang, Tan, Kaeling, Steenwyk, Jacob L., Colabardini, Ana Cristina, Ferreira Filho, Jaire A., de Castro, Patricia A., Silva, Lilian P., Preite, Nycolas W., Almeida, Fausto, de Assis, Leandro J., dos Santos, Renato A. C., Bowyer, Paul, Bromley, Michael, Owens, Rebecca A., Doyle, Sean, Demasi, Marilene, Hernández, Diego C. R., Netto, Luís Eduardo S., Pupo, Monica T., Rokas, Antonis, Loures, Flavio V., Wong, Koon H., Goldman, Gustavo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384679/
https://www.ncbi.nlm.nih.gov/pubmed/32667960
http://dx.doi.org/10.1371/journal.ppat.1008645

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