Proarrhythmogenic Effect of the L532P and N588K KCNH2 Mutations in the Human Heart Using a 3D Electrophysiological Model

BACKGROUND: Atrial arrhythmia is a cardiac disorder caused by abnormal electrical signaling and transmission, which can result in atrial fibrillation and eventual death. Genetic defects in ion channels can cause myocardial repolarization disorders. Arrhythmia-associated gene mutations, including KCN...

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Detalles Bibliográficos
Autores principales: Heikhmakhtiar, Aulia Khamas, Abrha, Abebe Tekle, Jeong, Da Un, Lim, Ki Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384902/
https://www.ncbi.nlm.nih.gov/pubmed/32715669
http://dx.doi.org/10.3346/jkms.2020.35.e238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7384902/
https://www.ncbi.nlm.nih.gov/pubmed/32715669
http://dx.doi.org/10.3346/jkms.2020.35.e238

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