Cargando…

Lipid Exchangers: Cellular Functions and Mechanistic Links With Phosphoinositide Metabolism

Lipids are amphiphilic molecules that self-assemble to form biological membranes. Thousands of lipid species coexist in the cell and, once combined, define organelle identity. Due to recent progress in lipidomic analysis, we now know how lipid composition is finely tuned in different subcellular reg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lipp, Nicolas-Frédéric, Ikhlef, Souade, Milanini, Julie, Drin, Guillaume
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385082/ https://www.ncbi.nlm.nih.gov/pubmed/32793602 http://dx.doi.org/10.3389/fcell.2020.00663

Ejemplares similares

Functional analyses of phosphatidylserine/PI(4)P exchangers with diverse lipid species and membrane contexts reveal unanticipated rules on lipid transfer
por: Ikhlef, Souade, et al.
Publicado: (2021)

In situ artificial contact sites (ISACS) between synthetic and endogenous organelle membranes allow for quantification of protein-tethering activities
por: Milanini, Julie, et al.
Publicado: (2022)

Regulation of phosphoinositide metabolism in Apicomplexan parasites
por: Arabiotorre, Angela, et al.
Publicado: (2023)

Phosphoinositide lipids in primary cilia biology
por: Conduit, Sarah E., et al.
Publicado: (2020)

Targeting phosphoinositide signaling in cancer: relevant techniques to study lipids and novel avenues for therapeutic intervention
por: Llorente, Alicia, et al.
Publicado: (2023)

Phosphoinositide Signaling and Mechanotransduction in Cardiovascular Biology and Disease
por: Krajnik, Amanda, et al.
Publicado: (2020)

Phosphoinositide Recognition Sites Are Blocked by Metabolite Attachment
por: Kervin, Troy A., et al.
Publicado: (2021)

Functions of Oxysterol-Binding Proteins at Membrane Contact Sites and Their Control by Phosphoinositide Metabolism
por: Nakatsu, Fubito, et al.
Publicado: (2021)

Modulation of Cellular Function by the Urokinase Receptor Signalling: A Mechanistic View
por: Alfano, Daniela, et al.
Publicado: (2022)

Monitoring Phosphoinositide Fluxes and Effectors During Leukocyte Chemotaxis and Phagocytosis
por: Montaño-Rendón, Fernando, et al.
Publicado: (2021)

Superresolution Microscopy Reveals Distinct Phosphoinositide Subdomains Within the Cilia Transition Zone
por: Conduit, Sarah E., et al.
Publicado: (2021)

Adult Muscle Stem Cells: Exploring the Links Between Systemic and Cellular Metabolism
por: Purohit, Gunjan, et al.
Publicado: (2019)

When PIP(2) Meets p53: Nuclear Phosphoinositide Signaling in the DNA Damage Response
por: Wang, Yu-Hsiu, et al.
Publicado: (2022)

Mechanisms of Non-Vesicular Exchange of Lipids at Membrane Contact Sites: Of Shuttles, Tunnels and, Funnels
por: Egea, Pascal F.
Publicado: (2021)

Mechanistic and Therapeutic Implications of Extracellular Vesicles as a Potential Link Between Covid-19 and Cardiovascular Disease Manifestations
por: Pironti, Gianluigi, et al.
Publicado: (2021)

Mechanistic Target of Rapamycin Inhibitors in Renal Cell Carcinoma: Potential, Limitations, and Perspectives
por: Faes, Seraina, et al.
Publicado: (2021)

Genetics, Epigenetics, Cellular Immunology, and Gut Microbiota: Emerging Links With Graves’ Disease
por: Zhou, Fangyu, et al.
Publicado: (2022)

Mechanistic Insight Into the Roles of Integrins in Osteoarthritis
por: Jin, Hongfu, et al.
Publicado: (2021)

A Quantitative Analysis of Cellular Lipid Compositions During Acute Proteotoxic ER Stress Reveals Specificity in the Production of Asymmetric Lipids
por: Reinhard, John, et al.
Publicado: (2020)

FcγRIIb-SHIP2 axis links Aβ to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model
por: Kam, Tae-In, et al.
Publicado: (2016)

Reconstitution of ORP-mediated lipid exchange process coupled to PI(4)P metabolism
por: Fuggetta, Nicolas, et al.
Publicado: (2023)

Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes
por: Giridharan, Sai Srinivas Panapakkam, et al.
Publicado: (2022)

Therapeutic and Mechanistic Perspectives of Protein Complexes in Breast Cancer
por: Waterhouse, Mark P., et al.
Publicado: (2019)

Mechanistic Drivers of Müllerian Duct Development and Differentiation Into the Oviduct
por: Santana Gonzalez, Laura, et al.
Publicado: (2021)

Transport Pathways That Contribute to the Cellular Distribution of Phosphatidylserine
por: Lenoir, Guillaume, et al.
Publicado: (2021)

Lipid rafts: linking prion protein to zinc transport and amyloid-β toxicity in Alzheimer's disease
por: Watt, Nicole T., et al.
Publicado: (2014)

Lipid metabolism and tumor immunotherapy
por: Wang, Yue, et al.
Publicado: (2023)

Lipid Metabolism at Membrane Contacts: Dynamics and Functions Beyond Lipid Homeostasis
por: Xu, Jiesi, et al.
Publicado: (2020)

Mechanism of Activation of Mechanistic Target of Rapamycin Complex 1 by Methionine
por: Kitada, Munehiro, et al.
Publicado: (2020)

Histone Deacetylases (HDACs) and Atherosclerosis: A Mechanistic and Pharmacological Review
por: Chen, Xiaona, et al.
Publicado: (2020)

New mechanistic insights into the RAS-SIN1 interaction at the membrane
por: Pudewell, Silke, et al.
Publicado: (2022)

SIRT7 and hepatic lipid metabolism
por: Tang, Bor Luen
Publicado: (2015)

Interplay Between Lipid Metabolism and Autophagy
por: Xie, Yangchun, et al.
Publicado: (2020)

A Journey on Extracellular Vesicles for Matrix Metalloproteinases: A Mechanistic Perspective
por: Thuault, Sylvie, et al.
Publicado: (2022)

Editorial: Mechanistic studies of genome integrity, environmental health, and cancer etiology
por: Yan, Shan, et al.
Publicado: (2022)

Class I PI3K Provide Lipid Substrate in T Cell Autophagy Through Linked Activity of Inositol Phosphatases
por: McLeod, Ian X., et al.
Publicado: (2021)

Mechanistic Insights From Single-Molecule Studies of Repair of Double Strand Breaks
por: Kong, Muwen, et al.
Publicado: (2021)

Mechanistic insights into genomic structure and functions of a novel oncogene YEATS4
por: Xian, Qingqing, et al.
Publicado: (2023)

Dysfunctional peroxisomal lipid metabolisms and their ocular manifestations
por: Chen, Chuck T., et al.
Publicado: (2022)

An electrostatic switching mechanism to control the lipid transfer activity of Osh6p
por: Lipp, Nicolas-Frédéric, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_51sgje62na9h9vnf65p94eupj4