Landscape of snake’ sex chromosomes evolution spanning 85 MYR reveals ancestry of sequences despite distinct evolutionary trajectories

Most of snakes exhibit a ZZ/ZW sex chromosome system, with different stages of degeneration. However, undifferentiated sex chromosomes and unique Y sex-linked markers, suggest that an XY system has also evolved in ancestral lineages. Comparative cytogenetic mappings revealed that several genes share...

Descripción completa

Detalles Bibliográficos
Autores principales: Viana, Patrik F., Ezaz, Tariq, de Bello Cioffi, Marcelo, Liehr, Thomas, Al-Rikabi, Ahmed, Goll, Leonardo G., Rocha, Anderson M., Feldberg, Eliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385105/
https://www.ncbi.nlm.nih.gov/pubmed/32719365
http://dx.doi.org/10.1038/s41598-020-69349-5
_version_ 1783563711877742592
author Viana, Patrik F.
Ezaz, Tariq
de Bello Cioffi, Marcelo
Liehr, Thomas
Al-Rikabi, Ahmed
Goll, Leonardo G.
Rocha, Anderson M.
Feldberg, Eliana
author_facet Viana, Patrik F.
Ezaz, Tariq
de Bello Cioffi, Marcelo
Liehr, Thomas
Al-Rikabi, Ahmed
Goll, Leonardo G.
Rocha, Anderson M.
Feldberg, Eliana
author_sort Viana, Patrik F.
collection PubMed
description Most of snakes exhibit a ZZ/ZW sex chromosome system, with different stages of degeneration. However, undifferentiated sex chromosomes and unique Y sex-linked markers, suggest that an XY system has also evolved in ancestral lineages. Comparative cytogenetic mappings revealed that several genes share ancestry among X, Y and Z chromosomes, implying that XY and ZW may have undergone transitions during serpent’s evolution. In this study, we performed a comparative cytogenetic analysis to identify homologies of sex chromosomes across ancestral (Henophidia) and more recent (Caenophidia) snakes. Our analysis suggests that, despite ~ 85 myr of independent evolution, henophidians and caenophidians retained conserved synteny over much of their genomes. However, our findings allowed us to discover that ancestral and recent lineages of snakes do not share the same sex chromosome and followed distinct pathways for sex chromosomes evolution.
format Online
Article
Text
id pubmed-7385105
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-73851052020-07-28 Landscape of snake’ sex chromosomes evolution spanning 85 MYR reveals ancestry of sequences despite distinct evolutionary trajectories Viana, Patrik F. Ezaz, Tariq de Bello Cioffi, Marcelo Liehr, Thomas Al-Rikabi, Ahmed Goll, Leonardo G. Rocha, Anderson M. Feldberg, Eliana Sci Rep Article Most of snakes exhibit a ZZ/ZW sex chromosome system, with different stages of degeneration. However, undifferentiated sex chromosomes and unique Y sex-linked markers, suggest that an XY system has also evolved in ancestral lineages. Comparative cytogenetic mappings revealed that several genes share ancestry among X, Y and Z chromosomes, implying that XY and ZW may have undergone transitions during serpent’s evolution. In this study, we performed a comparative cytogenetic analysis to identify homologies of sex chromosomes across ancestral (Henophidia) and more recent (Caenophidia) snakes. Our analysis suggests that, despite ~ 85 myr of independent evolution, henophidians and caenophidians retained conserved synteny over much of their genomes. However, our findings allowed us to discover that ancestral and recent lineages of snakes do not share the same sex chromosome and followed distinct pathways for sex chromosomes evolution. Nature Publishing Group UK 2020-07-27 /pmc/articles/PMC7385105/ /pubmed/32719365 http://dx.doi.org/10.1038/s41598-020-69349-5 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Viana, Patrik F.
Ezaz, Tariq
de Bello Cioffi, Marcelo
Liehr, Thomas
Al-Rikabi, Ahmed
Goll, Leonardo G.
Rocha, Anderson M.
Feldberg, Eliana
Landscape of snake’ sex chromosomes evolution spanning 85 MYR reveals ancestry of sequences despite distinct evolutionary trajectories
title Landscape of snake’ sex chromosomes evolution spanning 85 MYR reveals ancestry of sequences despite distinct evolutionary trajectories
title_full Landscape of snake’ sex chromosomes evolution spanning 85 MYR reveals ancestry of sequences despite distinct evolutionary trajectories
title_fullStr Landscape of snake’ sex chromosomes evolution spanning 85 MYR reveals ancestry of sequences despite distinct evolutionary trajectories
title_full_unstemmed Landscape of snake’ sex chromosomes evolution spanning 85 MYR reveals ancestry of sequences despite distinct evolutionary trajectories
title_short Landscape of snake’ sex chromosomes evolution spanning 85 MYR reveals ancestry of sequences despite distinct evolutionary trajectories
title_sort landscape of snake’ sex chromosomes evolution spanning 85 myr reveals ancestry of sequences despite distinct evolutionary trajectories
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385105/
https://www.ncbi.nlm.nih.gov/pubmed/32719365
http://dx.doi.org/10.1038/s41598-020-69349-5
work_keys_str_mv AT vianapatrikf landscapeofsnakesexchromosomesevolutionspanning85myrrevealsancestryofsequencesdespitedistinctevolutionarytrajectories
AT ezaztariq landscapeofsnakesexchromosomesevolutionspanning85myrrevealsancestryofsequencesdespitedistinctevolutionarytrajectories
AT debellocioffimarcelo landscapeofsnakesexchromosomesevolutionspanning85myrrevealsancestryofsequencesdespitedistinctevolutionarytrajectories
AT liehrthomas landscapeofsnakesexchromosomesevolutionspanning85myrrevealsancestryofsequencesdespitedistinctevolutionarytrajectories
AT alrikabiahmed landscapeofsnakesexchromosomesevolutionspanning85myrrevealsancestryofsequencesdespitedistinctevolutionarytrajectories
AT gollleonardog landscapeofsnakesexchromosomesevolutionspanning85myrrevealsancestryofsequencesdespitedistinctevolutionarytrajectories
AT rochaandersonm landscapeofsnakesexchromosomesevolutionspanning85myrrevealsancestryofsequencesdespitedistinctevolutionarytrajectories
AT feldbergeliana landscapeofsnakesexchromosomesevolutionspanning85myrrevealsancestryofsequencesdespitedistinctevolutionarytrajectories

Ejemplares similares