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Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs
Glycinergic synapses play a central role in motor control and pain processing in the central nervous system. Glycine receptors (GlyRs) are key players in mediating fast inhibitory neurotransmission at these synapses. While previous high-resolution structures have provided insights into the molecular...
Autores principales: | Kumar, Arvind, Basak, Sandip, Rao, Shanlin, Gicheru, Yvonne, Mayer, Megan L., Sansom, Mark S. P., Chakrapani, Sudha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385131/ https://www.ncbi.nlm.nih.gov/pubmed/32719334 http://dx.doi.org/10.1038/s41467-020-17364-5 |
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