Cargando…

An optogenetic system to control membrane phospholipid asymmetry through flippase activation in budding yeast

Lipid asymmetry in biological membranes is essential for various cell functions, such as cell polarity, cytokinesis, and apoptosis. P4-ATPases (flippases) are involved in the generation of such asymmetry. In Saccharomyces cerevisiae, the protein kinases Fpk1p/Fpk2p activate the P4-ATPases Dnf1p/Dnf2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Suzuki, Tomomi, Mioka, Tetsuo, Tanaka, Kazuma, Nagatani, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385178/ https://www.ncbi.nlm.nih.gov/pubmed/32719316 http://dx.doi.org/10.1038/s41598-020-69459-0

Ejemplares similares

Inositol Depletion Restores Vesicle Transport in Yeast Phospholipid Flippase Mutants
por: Yamagami, Kanako, et al.
Publicado: (2015)

Phospholipid flippases and Sfk1p, a novel regulator of phospholipid asymmetry, contribute to low permeability of the plasma membrane
por: Mioka, Tetsuo, et al.
Publicado: (2018)

Asymmetric distribution of phosphatidylserine is generated in the absence of phospholipid flippases in Saccharomyces cerevisiae
por: Mioka, Tetsuo, et al.
Publicado: (2014)

Phospholipid flippases and Sfk1 are essential for the retention of ergosterol in the plasma membrane
por: Kishimoto, Takuma, et al.
Publicado: (2021)

Extracellular vesicle budding is inhibited by redundant regulators of TAT-5 flippase localization and phospholipid asymmetry
por: Beer, Katharina B., et al.
Publicado: (2018)

Cfs1p, a Novel Membrane Protein in the PQ-Loop Family, Is Involved in Phospholipid Flippase Functions in Yeast
por: Yamamoto, Takaharu, et al.
Publicado: (2016)

A complex genetic interaction implicates that phospholipid asymmetry and phosphate homeostasis regulate Golgi functions
por: Miyasaka, Mamoru, et al.
Publicado: (2020)

The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane
por: Tanaka, Yoshiki, et al.
Publicado: (2016)

Regulation of membrane phospholipid asymmetry by Notch-mediated flippase expression controls the number of intraepithelial TCRαβ(+)CD8αα(+) T cells
por: Ishifune, Chieko, et al.
Publicado: (2019)

Regulation of phospholipid distribution in the lipid bilayer by flippases and scramblases
por: Sakuragi, Takaharu, et al.
Publicado: (2023)

P4-ATPases as Phospholipid Flippases—Structure, Function, and Enigmas
por: Andersen, Jens P., et al.
Publicado: (2016)

Model-guided optogenetic study of PKA signaling in budding yeast
por: Stewart-Ornstein, Jacob, et al.
Publicado: (2017)

Protein kinase Gin4 negatively regulates flippase function and controls plasma membrane asymmetry
por: Roelants, Françoise M., et al.
Publicado: (2015)

The ATPase activity of the phosphatidylethanolamine flippase TAT-5 inhibits extracellular vesicle budding from the plasma membrane
por: Pitts, Lauren R, et al.
Publicado: (2023)

The phospholipid flippase ALA3 regulates pollen tube growth and guidance in Arabidopsis
por: Yang, Yang, et al.
Publicado: (2022)

The phospholipid flippase ATP8B1 is required for lysosomal fusion in macrophages
por: Gómez‐Mellado, Valentina E., et al.
Publicado: (2022)

Gain-of-Function Mutations in the Phospholipid Flippase MprF Confer Specific Daptomycin Resistance
por: Ernst, Christoph M., et al.
Publicado: (2018)

A malaria parasite phospholipid flippase safeguards midgut traversal of ookinetes for mosquito transmission
por: Yang, Zhenke, et al.
Publicado: (2021)

Enzyme and phospholipid asymmetry in liver microsomal membranes
Publicado: (1977)

The Drosophila melanogaster Phospholipid Flippase dATP8B Is Required for Odorant Receptor Function
por: Liu, Yu-Chi, et al.
Publicado: (2014)

Proteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues
por: Wang, Jiao, et al.
Publicado: (2018)

Plasma membrane aminoglycerolipid flippase function is required for signaling competence in the yeast mating pheromone response pathway
por: Sartorel, Elodie, et al.
Publicado: (2015)

Protocol to purify and detect ubiquitinated phospholipids in budding yeast and human cell lines
por: Sakamaki, Jun-ichi, et al.
Publicado: (2022)

P4-ATPases: lipid flippases in cell membranes
por: Lopez-Marques, Rosa L., et al.
Publicado: (2013)

Physiological and Pathological Functions of TMEM30A: An Essential Subunit of P4-ATPase Phospholipid Flippases
por: Li, Jingyi, et al.
Publicado: (2023)

Cryo-EM of the ATP11C flippase reconstituted in Nanodiscs shows a distended phospholipid bilayer inner membrane around transmembrane helix 2
por: Nakanishi, Hanayo, et al.
Publicado: (2021)

Membrane Curvature, Trans-Membrane Area Asymmetry, Budding, Fission and Organelle Geometry
por: Mironov, Alexander A., et al.
Publicado: (2020)

Selective autophagy in budding yeast
por: Suzuki, Kuninori
Publicado: (2013)

Phospholipid flippases attenuate LPS-induced TLR4 signaling by mediating endocytic retrieval of Toll-like receptor 4
por: van der Mark, Vincent A., et al.
Publicado: (2016)

Phospholipid flippase ATP11C is endocytosed and downregulated following Ca(2+)-mediated protein kinase C activation
por: Takatsu, Hiroyuki, et al.
Publicado: (2017)

Dissection of GTPase-activating proteins reveals functional asymmetry in the COPI coat of budding yeast
por: Arakel, Eric C., et al.
Publicado: (2019)

C-terminus of the P4-ATPase ATP8A2 functions in protein folding and regulation of phospholipid flippase activity
por: Chalat, Madhavan, et al.
Publicado: (2017)

PUB11-Dependent Ubiquitination of the Phospholipid Flippase ALA10 Modifies ALA10 Localization and Affects the Pool of Linolenic Phosphatidylcholine
por: Salvaing, Juliette, et al.
Publicado: (2020)

Pros and cons of phospholipid asymmetry in erythrocytes
por: Sathi, Aiswarya, et al.
Publicado: (2014)

Lipid Flippases for Bacterial Peptidoglycan Biosynthesis
por: Ruiz, Natividad
Publicado: (2016)

Budding and Division of Giant Vesicles Linked to Phospholipid Production
por: Castro, Juan M., et al.
Publicado: (2019)

Asymmetry of the Budding Yeast Tem1 GTPase at Spindle Poles Is Required for Spindle Positioning But Not for Mitotic Exit
por: Scarfone, Ilaria, et al.
Publicado: (2015)

Acyl chain asymmetry and polyunsaturation of brain phospholipids facilitate membrane vesiculation without leakage
por: Manni, Marco M, et al.
Publicado: (2018)

An auxiliary, membrane-based mechanism for nuclear migration in budding yeast
por: Kirchenbauer, Marisa, et al.
Publicado: (2013)

P4 ATPases: Flippases in Health and Disease
por: van der Mark, Vincent A., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_pc58keabjq00g1o82pld2tal8s