Mapping of host-parasite-microbiome interactions reveals metabolic determinants of tropism and tolerance in Chagas disease

Chagas disease (CD) is a parasitic disease caused by Trypanosoma cruzi protozoa, presenting with cardiomyopathy, megaesophagus, and/or megacolon. To determine the mechanisms of gastrointestinal (GI) CD tissue tropism, we systematically characterized the spatial localization of infection-induced meta...

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Detalles Bibliográficos
Autores principales: Hossain, E., Khanam, S., Dean, D. A., Wu, C., Lostracco-Johnson, S., Thomas, D., Kane, S. S., Parab, A. R., Flores, K., Katemauswa, M., Gosmanov, C., Hayes, S. E., Zhang, Y., Li, D., Woelfel-Monsivais, C., Sankaranarayanan, K., McCall, L.-I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385396/
https://www.ncbi.nlm.nih.gov/pubmed/32766448
http://dx.doi.org/10.1126/sciadv.aaz2015

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