The clonal repopulation of HSPC gene modified with anti–HIV-1 RNAi is not affected by preexisting HIV-1 infection

Despite advances in hematopoietic stem/progenitor cell (HSPC) transplant for HIV-1–infected patients, the impact of a preexisting HIV-1 infection on the engraftment and clonal repopulation of HSPCs remains poorly understood. We have developed a long terminal repeat indexing-mediated integration site...

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Detalles Bibliográficos
Autores principales: Suryawanshi, Gajendra W., Khamaikawin, Wannisa, Wen, Jing, Shimizu, Saki, Arokium, Hubert, Xie, Yiming, Wang, Eugene, Kim, Shihyoung, Choi, Hyewon, Zhang, Chong, Yu, Hannah, Presson, Angela P., Kim, Namshin, An, Dong-Sung, Chen, Irvin S. Y., Kim, Sanggu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385479/
https://www.ncbi.nlm.nih.gov/pubmed/32766447
http://dx.doi.org/10.1126/sciadv.aay9206

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