Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

Clinical development of the COVID-19 vaccine candidate ChAdOx1 nCoV-19, a replication-deficient simian adenoviral vector expressing the full-length SARS-CoV-2 spike (S) protein was initiated in April 2020 following non-human primate studies using a single immunisation. Here, we compared the immunoge...

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Detalles Bibliográficos
Autores principales: Graham, Simon P., McLean, Rebecca K., Spencer, Alexandra J., Belij-Rammerstorfer, Sandra, Wright, Daniel, Ulaszewska, Marta, Edwards, Jane C., Hayes, Jack W. P., Martini, Veronica, Thakur, Nazia, Conceicao, Carina, Dietrich, Isabelle, Shelton, Holly, Waters, Ryan, Ludi, Anna, Wilsden, Ginette, Browning, Clare, Bialy, Dagmara, Bhat, Sushant, Stevenson-Leggett, Phoebe, Hollinghurst, Philippa, Gilbride, Ciaran, Pulido, David, Moffat, Katy, Sharpe, Hannah, Allen, Elizabeth, Mioulet, Valerie, Chiu, Chris, Newman, Joseph, Asfor, Amin S., Burman, Alison, Crossley, Sylvia, Huo, Jiandong, Owens, Raymond J., Carroll, Miles, Hammond, John A., Tchilian, Elma, Bailey, Dalan, Charleston, Bryan, Gilbert, Sarah C., Tuthill, Tobias J., Lambe, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385486/
https://www.ncbi.nlm.nih.gov/pubmed/32793398
http://dx.doi.org/10.1038/s41541-020-00221-3

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