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TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing
The PIWI protein MIWI2 and its associated PIWI-interacting RNAs (piRNAs) instruct DNA methylation of young active transposable elements (TEs) in the male germline. piRNAs are proposed to recruit MIWI2 to the transcriptionally active TE loci by base pairing to nascent transcripts, however the downstr...
Autores principales: | Schöpp, Theresa, Zoch, Ansgar, Berrens, Rebecca V., Auchynnikava, Tania, Kabayama, Yuka, Vasiliauskaitė, Lina, Rappsilber, Juri, Allshire, Robin C., O’Carroll, Dónal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385494/ https://www.ncbi.nlm.nih.gov/pubmed/32719317 http://dx.doi.org/10.1038/s41467-020-17372-5 |
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