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NUDT15 gene variants and thiopurine-induced leukopenia in patients with inflammatory bowel disease
Thiopurine has been used to maintain remission and to reduce antidrug antibody formation in monoclonal antibody therapy in patients with inflammatory bowel disease (IBD). The use of thiopurine is limited by side effects such as leukopenia. Thiopurine S-methyltransferase (TPMT) variants are associate...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Korean Association for the Study of Intestinal Diseases
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385579/ https://www.ncbi.nlm.nih.gov/pubmed/32482022 http://dx.doi.org/10.5217/ir.2020.00002 |