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Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd
Mfd couples transcription to nucleotide excision repair, and acts on RNA polymerases when elongation is impeded. Depending on impediment severity, this action results in either transcription termination or elongation rescue, which rely on ATP-dependent Mfd translocation on DNA. Due to its role in an...
Autores principales: | Brugger, Christiane, Zhang, Cheng, Suhanovsky, Margaret M., Kim, David D., Sinclair, Amy N., Lyumkis, Dmitry, Deaconescu, Alexandra M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385628/ https://www.ncbi.nlm.nih.gov/pubmed/32719356 http://dx.doi.org/10.1038/s41467-020-17457-1 |
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