The PI3K/AKT/mTOR pathway regulates autophagy to induce apoptosis of alveolar epithelial cells in chronic obstructive pulmonary disease caused by PM2.5 particulate matter

OBJECTIVE: Many lung diseases are associated with changes in autophagic activity. The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway plays a key regulatory role in autophagy. Our aim was to explore the function of PI3K/AKT/mTOR path...

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Detalles Bibliográficos
Autores principales: Zhang, Fang, Ma, Hui, Wang, Zhong Lan, Li, Wei Hua, Liu, Hua, Zhao, Yan Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Pre-Clinical Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385846/
https://www.ncbi.nlm.nih.gov/pubmed/32715876
http://dx.doi.org/10.1177/0300060520927919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385846/
https://www.ncbi.nlm.nih.gov/pubmed/32715876
http://dx.doi.org/10.1177/0300060520927919

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