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EZH2: a novel target for cancer treatment

Enhancer of zeste homolog 2 (EZH2) is enzymatic catalytic subunit of polycomb repressive complex 2 (PRC2) that can alter downstream target genes expression by trimethylation of Lys-27 in histone 3 (H3K27me3). EZH2 could also regulate gene expression in ways besides H3K27me3. Functions of EZH2 in cel...

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Detalles Bibliográficos
Autores principales: Duan, Ran, Du, Wenfang, Guo, Weijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385862/
https://www.ncbi.nlm.nih.gov/pubmed/32723346
http://dx.doi.org/10.1186/s13045-020-00937-8

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