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Targeting PPARα in the rat valproic acid model of autism: focus on social motivational impairment and sex-related differences
BACKGROUND: The social motivational theory of autism spectrum disorder (ASD) focuses on social anhedonia as key causal feature of the impaired peer relationships that characterize ASD patients. ASD prevalence is higher in boys, but increasing evidence suggests underdiagnosis and undertreatment in gi...
Autores principales: | Scheggi, Simona, Guzzi, Francesca, Braccagni, Giulia, De Montis, Maria Graziella, Parenti, Marco, Gambarana, Carla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385875/ https://www.ncbi.nlm.nih.gov/pubmed/32718349 http://dx.doi.org/10.1186/s13229-020-00358-x |
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