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The pharmacological and clinical aspects behind dose loading of biological disease modifying anti-rheumatic drugs (bDMARDs) in auto-immune rheumatic diseases (AIRDs): rationale and systematic narrative review of clinical evidence

BACKGROUND: Dose loading of biological disease modifying anti-rheumatic drugs (bDMARDs) in auto-immune rheumatic diseases (AIRDs) is performed to achieve steady state drug concentrations earlier after treatment start compared to dosing regimens without loading. Although loading inherently results in...

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Detalles Bibliográficos
Autores principales:	Geurts-Voerman, Gerlienke E., Verhoef, Lise M., van den Bemt, Bart J. F., den Broeder, Alfons A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7385956/ https://www.ncbi.nlm.nih.gov/pubmed/32743343 http://dx.doi.org/10.1186/s41927-020-00130-x

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