Transformation of Mature Osteoblasts into Bone Lining Cells and RNA Sequencing-Based Transcriptome Profiling of Mouse Bone during Mechanical Unloading

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BACKGROUND: We investigated RNA sequencing-based transcriptome profiling and the transformation of mature osteoblasts into bone lining cells (BLCs) through a lineage tracing study to better understand the effect of mechanical unloading on bone loss. METHODS: Dmp1-CreERt2(+):Rosa26R mice were injecte...

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Detalles Bibliográficos
Autores principales: Hong, A Ram, Kim, Kwangsoo, Lee, Ji Yeon, Yang, Jae-Yeon, Kim, Jung Hee, Shin, Chan Soo, Kim, Sang Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386115/
https://www.ncbi.nlm.nih.gov/pubmed/32615730
http://dx.doi.org/10.3803/EnM.2020.35.2.456
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