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Species-Specificity of Transcriptional Regulation and the Response to Lipopolysaccharide in Mammalian Macrophages
Mammalian macrophages differ in their basal gene expression profiles and response to the toll-like receptor 4 (TLR4) agonist, lipopolysaccharide (LPS). In human macrophages, LPS elicits a temporal cascade of transient gene expression including feed forward activators and feedback regulators that lim...
Autores principales: | Bush, Stephen J., McCulloch, Mary E. B., Lisowski, Zofia M., Muriuki, Charity, Clark, Emily L., Young, Rachel, Pridans, Clare, Prendergast, James G. D., Summers, Kim M., Hume, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386301/ https://www.ncbi.nlm.nih.gov/pubmed/32793601 http://dx.doi.org/10.3389/fcell.2020.00661 |
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