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Research on viral agents associated with feline reproductive problems reveals a high association with feline panleukopenia virus

Although reproductive failures (RF) such as abortion, stillbirth and neonatal mortality in cats are still under researched, it is known that many RF are caused by viral agents. This research surveyed the viral agent prevalence in queens with RF. Queens were excluded from the study if their RF was ca...

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Autores principales: Oliveira, Ilanna Vanessa Pristo de Medeiros, Freire, Débora Alves de Carvalho, Ferreira, Heider Irinaldo Pereira, Moura, Gabriela Hemylin Ferreira, da Rocha, Célio Souza, Calabuig, Cecilia Irene Pérez, Kurissio, Jacqueline Kazue, Junior, João Pessoa Araújo, Antunes, João Marcelo Azevedo de Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386638/
https://www.ncbi.nlm.nih.gov/pubmed/32734056
http://dx.doi.org/10.1016/j.vas.2018.06.004
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author Oliveira, Ilanna Vanessa Pristo de Medeiros
Freire, Débora Alves de Carvalho
Ferreira, Heider Irinaldo Pereira
Moura, Gabriela Hemylin Ferreira
da Rocha, Célio Souza
Calabuig, Cecilia Irene Pérez
Kurissio, Jacqueline Kazue
Junior, João Pessoa Araújo
Antunes, João Marcelo Azevedo de Paula
author_facet Oliveira, Ilanna Vanessa Pristo de Medeiros
Freire, Débora Alves de Carvalho
Ferreira, Heider Irinaldo Pereira
Moura, Gabriela Hemylin Ferreira
da Rocha, Célio Souza
Calabuig, Cecilia Irene Pérez
Kurissio, Jacqueline Kazue
Junior, João Pessoa Araújo
Antunes, João Marcelo Azevedo de Paula
author_sort Oliveira, Ilanna Vanessa Pristo de Medeiros
collection PubMed
description Although reproductive failures (RF) such as abortion, stillbirth and neonatal mortality in cats are still under researched, it is known that many RF are caused by viral agents. This research surveyed the viral agent prevalence in queens with RF. Queens were excluded from the study if their RF was caused by issues other than infection, such as genetic, traumatic, hormonal or nutritional problems, or if they had a history of RF. Blood samples from 26 pregnant females with RF were collected for complete blood counts (BCC), renal/hepatic biochemistry and glycaemic analysis. Ultrasonography was performed to evaluate gestational age and foetal viability. When possible, placentas, humours and foetal tissues were collected. Blood samples were tested by PCR and qPCR for feline leukaemia virus (FeLV), feline immunodeficiency virus (FIV), feline alphaherpesvirus 1 (FeHV-1) and carnivore protoparvovirus 1 (CPPV-1). All maternal samples were negative for FeLV, FIV and FeHV-1 and positive for CPPV-1. In addition, foetuses from one queen and three females were positive for CPPV-1 by qPCR and for feline panleukopenia virus (FPV) through DNA sequencing. The BCC and biochemistry results revealed significant neutrophilia, lymphopenia, monocytosis, and liver enzymes. These results provide the first description of an FPV agent causing only RF-related clinical signs in queens.
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spelling pubmed-73866382020-07-29 Research on viral agents associated with feline reproductive problems reveals a high association with feline panleukopenia virus Oliveira, Ilanna Vanessa Pristo de Medeiros Freire, Débora Alves de Carvalho Ferreira, Heider Irinaldo Pereira Moura, Gabriela Hemylin Ferreira da Rocha, Célio Souza Calabuig, Cecilia Irene Pérez Kurissio, Jacqueline Kazue Junior, João Pessoa Araújo Antunes, João Marcelo Azevedo de Paula Vet Anim Sci Article Although reproductive failures (RF) such as abortion, stillbirth and neonatal mortality in cats are still under researched, it is known that many RF are caused by viral agents. This research surveyed the viral agent prevalence in queens with RF. Queens were excluded from the study if their RF was caused by issues other than infection, such as genetic, traumatic, hormonal or nutritional problems, or if they had a history of RF. Blood samples from 26 pregnant females with RF were collected for complete blood counts (BCC), renal/hepatic biochemistry and glycaemic analysis. Ultrasonography was performed to evaluate gestational age and foetal viability. When possible, placentas, humours and foetal tissues were collected. Blood samples were tested by PCR and qPCR for feline leukaemia virus (FeLV), feline immunodeficiency virus (FIV), feline alphaherpesvirus 1 (FeHV-1) and carnivore protoparvovirus 1 (CPPV-1). All maternal samples were negative for FeLV, FIV and FeHV-1 and positive for CPPV-1. In addition, foetuses from one queen and three females were positive for CPPV-1 by qPCR and for feline panleukopenia virus (FPV) through DNA sequencing. The BCC and biochemistry results revealed significant neutrophilia, lymphopenia, monocytosis, and liver enzymes. These results provide the first description of an FPV agent causing only RF-related clinical signs in queens. Elsevier 2018-07-02 /pmc/articles/PMC7386638/ /pubmed/32734056 http://dx.doi.org/10.1016/j.vas.2018.06.004 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Oliveira, Ilanna Vanessa Pristo de Medeiros
Freire, Débora Alves de Carvalho
Ferreira, Heider Irinaldo Pereira
Moura, Gabriela Hemylin Ferreira
da Rocha, Célio Souza
Calabuig, Cecilia Irene Pérez
Kurissio, Jacqueline Kazue
Junior, João Pessoa Araújo
Antunes, João Marcelo Azevedo de Paula
Research on viral agents associated with feline reproductive problems reveals a high association with feline panleukopenia virus
title Research on viral agents associated with feline reproductive problems reveals a high association with feline panleukopenia virus
title_full Research on viral agents associated with feline reproductive problems reveals a high association with feline panleukopenia virus
title_fullStr Research on viral agents associated with feline reproductive problems reveals a high association with feline panleukopenia virus
title_full_unstemmed Research on viral agents associated with feline reproductive problems reveals a high association with feline panleukopenia virus
title_short Research on viral agents associated with feline reproductive problems reveals a high association with feline panleukopenia virus
title_sort research on viral agents associated with feline reproductive problems reveals a high association with feline panleukopenia virus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386638/
https://www.ncbi.nlm.nih.gov/pubmed/32734056
http://dx.doi.org/10.1016/j.vas.2018.06.004
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