Blockade of programmed cell death protein 1 (PD-1) in Sézary syndrome reduces Th2 phenotype of non-tumoral T lymphocytes but may enhance tumor proliferation

Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphoma (L-CTCL) that arises from malignant clonally derived skin-homing CD4(+) T cells. Based on advancements in our understanding of the mechanisms underlying L-CTCL, boosting the suppressed immune response emerges as a pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Saulite, Ieva, Ignatova, Desislava, Chang, Yun-Tsan, Fassnacht, Christina, Dimitriou, Florentia, Varypataki, Eleni, Anzengruber, Florian, Nägeli, Mirjam, Cozzio, Antonio, Dummer, Reinhard, Scarisbrick, Julia, Pascolo, Steve, Hoetzenecker, Wolfram, Bobrowicz, Malgorzata, Guenova, Emmanuella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386859/
https://www.ncbi.nlm.nih.gov/pubmed/32760603
http://dx.doi.org/10.1080/2162402X.2020.1738797

Ejemplares similares

Ejemplares similares