Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity

RATIONALE: Endothelial cells (ECs) are highly glycolytic and generate the majority of their energy via the breakdown of glucose to lactate. At the same time, a main role of ECs is to allow the transport of glucose to the surrounding tissues. GLUT1 (glucose transporter isoform 1/Slc2a1) is highly exp...

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Detalles Bibliográficos
Autores principales: Veys, Koen, Fan, Zheng, Ghobrial, Moheb, Bouché, Ann, García-Caballero, Melissa, Vriens, Kim, Conchinha, Nadine Vasconcelos, Seuwen, Aline, Schlegel, Felix, Gorski, Tatiane, Crabbé, Melissa, Gilardoni, Paola, Ardicoglu, Raphaela, Schaffenrath, Johanna, Casteels, Cindy, De Smet, Gino, Smolders, Ilse, Van Laere, Koen, Abel, E. Dale, Fendt, Sarah-Maria, Schroeter, Aileen, Kalucka, Joanna, Cantelmo, Anna Rita, Wälchli, Thomas, Keller, Annika, Carmeliet, Peter, De Bock, Katrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386868/
https://www.ncbi.nlm.nih.gov/pubmed/32404031
http://dx.doi.org/10.1161/CIRCRESAHA.119.316463

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