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Inhibition of miRNA-135a-5p ameliorates TGF-β1-induced human renal fibrosis by targeting SIRT1 in diabetic nephropathy

miRNA-135a-5p upregulation has been identified in renal fibrosis in diabetic nephropathy (DN) with an incompletely known mechanism. Previous data showed that Sirtuin 1 (SIRT1) serves as a novel therapeutic target for DN and interact with the transforming growth factor-β/mothers against decapentapleg...

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Detalles Bibliográficos
Autores principales:	Zhang, Juan, Zhang, Lian, Zha, Dongqing, Wu, Xiaoyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387088/ https://www.ncbi.nlm.nih.gov/pubmed/32705273 http://dx.doi.org/10.3892/ijmm.2020.4647

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