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Age-related shift in LTD is dependent on neuronal adenosine A(2A) receptors interplay with mGluR5 and NMDA receptors

Synaptic dysfunction plays a central role in Alzheimer’s disease (AD), since it drives the cognitive decline. An association between a polymorphism of the adenosine A(2A) receptor (A(2A)R) encoding gene—ADORA2A, and hippocampal volume in AD patients was recently described. In this study, we explore...

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Detalles Bibliográficos
Autores principales:	Temido-Ferreira, Mariana, Ferreira, Diana G., Batalha, Vânia L., Marques-Morgado, Inês, Coelho, Joana E., Pereira, Pedro, Gomes, Rui, Pinto, Andreia, Carvalho, Sara, Canas, Paula M., Cuvelier, Laetitia, Buée-Scherrer, Valerie, Faivre, Emilie, Baqi, Younis, Müller, Christa E., Pimentel, José, Schiffmann, Serge N., Buée, Luc, Bader, Michael, Outeiro, Tiago F., Blum, David, Cunha, Rodrigo A., Marie, Hélène, Pousinha, Paula A., Lopes, Luísa V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387321/ https://www.ncbi.nlm.nih.gov/pubmed/29950682 http://dx.doi.org/10.1038/s41380-018-0110-9

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