Cargando…
Global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys
People and other animals learn the values of choices by observing the contingencies between them and their outcomes. However, decisions are not guided by choice-linked reward associations alone; macaques also maintain a memory of the general, average reward rate – the global reward state – in an env...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387352/ https://www.ncbi.nlm.nih.gov/pubmed/32724052 http://dx.doi.org/10.1038/s41467-020-17343-w |
_version_ | 1783564103483129856 |
---|---|
author | Wittmann, Marco K. Fouragnan, Elsa Folloni, Davide Klein-Flügge, Miriam C. Chau, Bolton K. H. Khamassi, Mehdi Rushworth, Matthew F. S. |
author_facet | Wittmann, Marco K. Fouragnan, Elsa Folloni, Davide Klein-Flügge, Miriam C. Chau, Bolton K. H. Khamassi, Mehdi Rushworth, Matthew F. S. |
author_sort | Wittmann, Marco K. |
collection | PubMed |
description | People and other animals learn the values of choices by observing the contingencies between them and their outcomes. However, decisions are not guided by choice-linked reward associations alone; macaques also maintain a memory of the general, average reward rate – the global reward state – in an environment. Remarkably, global reward state affects the way that each choice outcome is valued and influences future decisions so that the impact of both choice success and failure is different in rich and poor environments. Successful choices are more likely to be repeated but this is especially the case in rich environments. Unsuccessful choices are more likely to be abandoned but this is especially likely in poor environments. Functional magnetic resonance imaging (fMRI) revealed two distinct patterns of activity, one in anterior insula and one in the dorsal raphe nucleus, that track global reward state as well as specific outcome events. |
format | Online Article Text |
id | pubmed-7387352 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-73873522020-08-12 Global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys Wittmann, Marco K. Fouragnan, Elsa Folloni, Davide Klein-Flügge, Miriam C. Chau, Bolton K. H. Khamassi, Mehdi Rushworth, Matthew F. S. Nat Commun Article People and other animals learn the values of choices by observing the contingencies between them and their outcomes. However, decisions are not guided by choice-linked reward associations alone; macaques also maintain a memory of the general, average reward rate – the global reward state – in an environment. Remarkably, global reward state affects the way that each choice outcome is valued and influences future decisions so that the impact of both choice success and failure is different in rich and poor environments. Successful choices are more likely to be repeated but this is especially the case in rich environments. Unsuccessful choices are more likely to be abandoned but this is especially likely in poor environments. Functional magnetic resonance imaging (fMRI) revealed two distinct patterns of activity, one in anterior insula and one in the dorsal raphe nucleus, that track global reward state as well as specific outcome events. Nature Publishing Group UK 2020-07-28 /pmc/articles/PMC7387352/ /pubmed/32724052 http://dx.doi.org/10.1038/s41467-020-17343-w Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Wittmann, Marco K. Fouragnan, Elsa Folloni, Davide Klein-Flügge, Miriam C. Chau, Bolton K. H. Khamassi, Mehdi Rushworth, Matthew F. S. Global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys |
title | Global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys |
title_full | Global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys |
title_fullStr | Global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys |
title_full_unstemmed | Global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys |
title_short | Global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys |
title_sort | global reward state affects learning and activity in raphe nucleus and anterior insula in monkeys |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387352/ https://www.ncbi.nlm.nih.gov/pubmed/32724052 http://dx.doi.org/10.1038/s41467-020-17343-w |
work_keys_str_mv | AT wittmannmarcok globalrewardstateaffectslearningandactivityinraphenucleusandanteriorinsulainmonkeys AT fouragnanelsa globalrewardstateaffectslearningandactivityinraphenucleusandanteriorinsulainmonkeys AT follonidavide globalrewardstateaffectslearningandactivityinraphenucleusandanteriorinsulainmonkeys AT kleinfluggemiriamc globalrewardstateaffectslearningandactivityinraphenucleusandanteriorinsulainmonkeys AT chauboltonkh globalrewardstateaffectslearningandactivityinraphenucleusandanteriorinsulainmonkeys AT khamassimehdi globalrewardstateaffectslearningandactivityinraphenucleusandanteriorinsulainmonkeys AT rushworthmatthewfs globalrewardstateaffectslearningandactivityinraphenucleusandanteriorinsulainmonkeys |