Intravital Imaging of Adoptive T-Cell Morphology, Mobility and Trafficking Following Immune Checkpoint Inhibition in a Mouse Melanoma Model

Efficient T-cell targeting, infiltration and activation within tumors is crucial for successful adoptive T-cell therapy. Intravital microscopy is a powerful tool for the visualization of T-cell behavior within tumors, as well as spatial and temporal heterogeneity in response to immunotherapy. Here w...

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Detalles Bibliográficos
Autores principales: Lau, Doreen, Garçon, Fabien, Chandra, Anita, Lechermann, Laura M., Aloj, Luigi, Chilvers, Edwin R., Corrie, Pippa G., Okkenhaug, Klaus, Gallagher, Ferdia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387409/
https://www.ncbi.nlm.nih.gov/pubmed/32793206
http://dx.doi.org/10.3389/fimmu.2020.01514

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