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Laparoscopic complete mesocolic excision with D3 lymph node dissection for right colon cancer in elderly patients

Complete mesocolic excision (CME) with D3 lymph node dissection is considered an oncological surgery for right colon cancer. However, there is still controversy for extensive oncological surgery in elderly patients. The aim of this study is to evaluate the safety and oncological outcomes of laparosc...

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Autores principales: Hwang, Duk Yeon, Lee, Gyeo Ra, Kim, Ji Hoon, Lee, Yoon Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387481/
https://www.ncbi.nlm.nih.gov/pubmed/32724111
http://dx.doi.org/10.1038/s41598-020-69617-4
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author Hwang, Duk Yeon
Lee, Gyeo Ra
Kim, Ji Hoon
Lee, Yoon Suk
author_facet Hwang, Duk Yeon
Lee, Gyeo Ra
Kim, Ji Hoon
Lee, Yoon Suk
author_sort Hwang, Duk Yeon
collection PubMed
description Complete mesocolic excision (CME) with D3 lymph node dissection is considered an oncological surgery for right colon cancer. However, there is still controversy for extensive oncological surgery in elderly patients. The aim of this study is to evaluate the safety and oncological outcomes of laparoscopic CME with D3 lymph node dissection for right colon cancer in elderly patients. Patients who underwent laparoscopic right colectomy, from 2004 to 2014, were divided into Groups A (age ≥ 70 years, n = 80) or B (age < 70 years, n = 127). Short and long-term outcomes were analysed. Basic demographics and short-term surgical outcomes were similar between groups. Among pathological outcomes, the mean number of harvested lymph nodes was significantly less in Group A. Adjuvant chemotherapy refusal rate was significantly higher in Group A. Overall and recurrence-free survival were similar between groups. We found laparoscopic CME with D3 lymph node dissection is a safe and feasible surgical option for right colon cancer in elderly patients.
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spelling pubmed-73874812020-07-29 Laparoscopic complete mesocolic excision with D3 lymph node dissection for right colon cancer in elderly patients Hwang, Duk Yeon Lee, Gyeo Ra Kim, Ji Hoon Lee, Yoon Suk Sci Rep Article Complete mesocolic excision (CME) with D3 lymph node dissection is considered an oncological surgery for right colon cancer. However, there is still controversy for extensive oncological surgery in elderly patients. The aim of this study is to evaluate the safety and oncological outcomes of laparoscopic CME with D3 lymph node dissection for right colon cancer in elderly patients. Patients who underwent laparoscopic right colectomy, from 2004 to 2014, were divided into Groups A (age ≥ 70 years, n = 80) or B (age < 70 years, n = 127). Short and long-term outcomes were analysed. Basic demographics and short-term surgical outcomes were similar between groups. Among pathological outcomes, the mean number of harvested lymph nodes was significantly less in Group A. Adjuvant chemotherapy refusal rate was significantly higher in Group A. Overall and recurrence-free survival were similar between groups. We found laparoscopic CME with D3 lymph node dissection is a safe and feasible surgical option for right colon cancer in elderly patients. Nature Publishing Group UK 2020-07-28 /pmc/articles/PMC7387481/ /pubmed/32724111 http://dx.doi.org/10.1038/s41598-020-69617-4 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Hwang, Duk Yeon
Lee, Gyeo Ra
Kim, Ji Hoon
Lee, Yoon Suk
Laparoscopic complete mesocolic excision with D3 lymph node dissection for right colon cancer in elderly patients
title Laparoscopic complete mesocolic excision with D3 lymph node dissection for right colon cancer in elderly patients
title_full Laparoscopic complete mesocolic excision with D3 lymph node dissection for right colon cancer in elderly patients
title_fullStr Laparoscopic complete mesocolic excision with D3 lymph node dissection for right colon cancer in elderly patients
title_full_unstemmed Laparoscopic complete mesocolic excision with D3 lymph node dissection for right colon cancer in elderly patients
title_short Laparoscopic complete mesocolic excision with D3 lymph node dissection for right colon cancer in elderly patients
title_sort laparoscopic complete mesocolic excision with d3 lymph node dissection for right colon cancer in elderly patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387481/
https://www.ncbi.nlm.nih.gov/pubmed/32724111
http://dx.doi.org/10.1038/s41598-020-69617-4
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