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In silico identification and functional validation of linear cationic α-helical antimicrobial peptides in the ascidian Ciona intestinalis

We developed a computing method to identify linear cationic α-helical antimicrobial peptides (LCAMPs) in the genome of Ciona intestinalis based on its structural and physicochemical features. Using this method, 22 candidates of Ciona LCAMPs, including well-known antimicrobial peptides, were identifi...

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Detalles Bibliográficos
Autores principales: Ohtsuka, Yukio, Inagaki, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387483/
https://www.ncbi.nlm.nih.gov/pubmed/32724213
http://dx.doi.org/10.1038/s41598-020-69485-y