The associations of BMI with mean diffusivity of basal ganglia among young adults with mild obesity and without obesity

Obesity causes a wide range of systemic diseases and is associated with mood and anxiety disorders. It is also associated with dopaminergic reward system function. However, the relationships between microstructural properties of the dopaminergic system and body mass index (BMI) have not been investi...

Descripción completa

Detalles Bibliográficos
Autores principales: Takeuchi, Hikarua, Taki, Yasuyuki, Nouchi, Rui, Yokoyama, Ryoichi, Nakagawa, Seishu, Iizuka, Kunio, Sakaki, Kohei, Araki, Tsuyoshi, Nozawa, Takayuki, Ikeda, Shigeyuki, Yokota, Susumu, Hanawa, Sugiko, Magistro, Daniele, Kotozaki, Yuka, Sasaki, Yukako, dos S. Kawata, Kelssy H., Kawashima, Ryuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387490/
https://www.ncbi.nlm.nih.gov/pubmed/32724120
http://dx.doi.org/10.1038/s41598-020-69438-5
Descripción
Sumario:Obesity causes a wide range of systemic diseases and is associated with mood and anxiety disorders. It is also associated with dopaminergic reward system function. However, the relationships between microstructural properties of the dopaminergic system and body mass index (BMI) have not been investigated. In this study, we investigated the associations of BMI with mean diffusivity (MD), diffusion tensor imaging measure in areas of the dopaminergic system (MDDS) in 435 healthy young adults with mild obesity and without obesity (BMI < 40). We detected the association between greater BMI and lower MD of the right globus pallidus and the right putamen. These results suggest that the property of the dopaminergic system is associated with BMI among young adults with mild obesity and without obesity.

Ejemplares similares