Cargando…
Hepatocytic transcriptional signatures predict comparative drug interaction potential of rifamycin antibiotics
Current strategies to treat tuberculosis (TB) and co-morbidities involve multidrug combination therapies. Rifamycin antibiotics are a key component of TB therapy and a common source of drug–drug interactions (DDIs) due to induction of drug metabolizing enzymes (DMEs). Management of rifamycin DDIs ar...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387492/ https://www.ncbi.nlm.nih.gov/pubmed/32724080 http://dx.doi.org/10.1038/s41598-020-69228-z |