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Comparison of Whole Genome (wg-) and Core Genome (cg-) MLST (BioNumerics(TM)) Versus SNP Variant Calling for Epidemiological Investigation of Pseudomonas aeruginosa

Whole genome sequencing (WGS) is increasingly used for epidemiological investigations of pathogens. While SNP variant calling is currently considered as the most suitable method, the choice of a representative reference genome and the isolate dependency of results limit standardization and affect re...

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Detalles Bibliográficos
Autores principales: Blanc, Dominique S., Magalhães, Bárbara, Koenig, Isabelle, Senn, Laurence, Grandbastien, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387498/
https://www.ncbi.nlm.nih.gov/pubmed/32793169
http://dx.doi.org/10.3389/fmicb.2020.01729